Results 41 to 50 of about 2,990,046 (310)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Effects of Annealing on Enthalpy Recovery and Nanomechanical Behaviors of a La-Based Bulk Metallic Glass

open access: yesMetals, 2021
Structural relaxation and nanomechanical behaviors of La65Al14Ni5Co5Cu9.2Ag1.8 bulk metallic glass (BMG) with a low glass transition temperature during annealing have been investigated by calorimetry and nanoindentation measurement.
Ting Shi, Lanping Huang, Song Li
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Impact of shadow glass transition on crystallization in metallic glass

open access: yesNational Science Open
The stability of glass against crystallization is of importance in practical applications and theoretical understanding of the nature of glass materials. Annealing has complicated influences on glass stability.
Zhang Hui-Ru   +4 more
doaj   +1 more source

Competition Between Entropy and Energy in Network Glass: The Hidden Connection Between Intermediate Phase and Liquid-Liquid Transition

open access: yesFrontiers in Materials, 2019
In network glass including chalcogenides, the network topology of microscopic structures can be tuned by changing the chemical compositions. As the composition is varied, an intermediate phase (IP) singularly different from the adjacent floppy or rigid ...
J. Quetzalcóatl Toledo-Marín, Le Yan
doaj   +1 more source

Exploratory Study on the Load-Bearing Behaviour of Laminated Glass Beams Exposed to Fire

open access: yes, 2022
All-glass structures have become increasingly popular with architects and builders in recent years. Glass surfaces are becoming larger and more impressive, while connections are being decreased to obtain maximum transparency.
Lohr, Katharina (author)   +2 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A novel method for characterizing temperature-dependent elastic modulus and glass transition temperature by processing the images of bending cantilever slender beams at different temperatures

open access: yesAIP Advances, 2018
We propose a novel method for estimating the elastic modulus of several materials by processing the bending image of cantilever material sheets. The calculated results (tested for five samples) were consistent with data obtained by direct measurement ...
Nadya Amalia   +6 more
doaj   +1 more source

Does Explicit Polarizability Improve Molecular Dynamics Predictions of Glass Transition Temperatures of Ionic Liquids? [PDF]

open access: yes, 2022
Molecular-dynamics simulations are used for predictions of the glass transition temperatures for a test set of 5 aprotic ionic liquids. Glass transitions are localized with the trend-shift method analyzing volumetric and transport properties of bulk ...
Ctirad, Cervinka, Martin, Klajmon
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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