Results 61 to 70 of about 703,544 (344)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Glass transition temperatures of pure glass-forming liquids and binary mixtures

Scientific Reports
The glass transition remains one of the most enduring and debated problems in condensed matter science, engaging researchers across disciplines. Two main approaches have traditionally been used to study the glass transition in pure glass formers and ...
Vitaly Kocherbitov, Ivan Argatov
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Solidification Properties of Polyalcohols Aqueous Solution Studied by DSC

Zhileng xuebao, 2005
In order to examine possible relations between freezing properties and the number of hydroxyl groups in solute molecules, a differential scanning calorimeter (Pyris- Diamond DSC) was employed to study the thermal behaviors of polyalcohols aqueous, such ...
胡桐记, 高才, 周国燕, 胥义, 华泽钊   +4 more
doaj   +2 more sources

Microscopic Theory of Heterogeneity and Non-Exponential Relaxations in Supercooled Liquids

, 2000
Recent experiments and computer simulations show that supercooled liquids around the glass transition temperature are "dynamically heterogeneous" [1]. Such heterogeneity is expected from the random first order transition theory of the glass transition ...
B. Bohmer, B. Castaing, C. Dasgupta, C. Donati, C. Monthus, D. J. Gross, E. Gardner, E. V. Russell, G. Adam, H. Sillescu, J. P. Stoessel, L. D. Landau, M. D. Ediger, M. H. Cohen, M. Mezard, M. Mezard, M. T. Cicerone, P. G. Wolynes, P. K. Dixon, Peter G. Wolynes, S. Buchner, T. R. Kirkpatrick, T. R. Kirkpatrick, T. R. Kirkpatrick, T. R. Kirkpatrick, U. Bengtzelius, U. Tracht, W. Gotze, W. Kauzmann, W. Kob, X. Xia, Xiaoyu Xia, Y. Singh   +32 more
core   +1 more source

Spin glasses in the limit of an infinite number of spin components [PDF]

, 2004
We consider the spin glass model in which the number of spin components, m, is infinite. In the formulation of the problem appropriate for numerical calculations proposed by several authors, we show that the order parameter defined by the long-distance ...
A. Dhar, A. J. Bray, A. P. Young, L. W. Lee   +3 more
core   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effect of Cutting Temperature on Bending Properties of Carbon Fibre Reinforced Plastics

Science and Engineering of Composite Materials, 2019
High cutting temperatures are easily generated during the machining of carbon fibre reinforced plastics (CFRP) and can induce serious damage during machining such as delamination. The purpose of this paper is to study the influence of cutting temperature
Wang Ben, Yang Bowen, Wang Minghai, Zheng Yaohui, Hong Xianjun, Zhang Fan   +5 more
doaj   +1 more source

The Phase Diagram of Random Heteropolymers

, 2004
We propose a new analytic approach to study the phase diagram of random heteropolymers, based on the cavity method. For copolymers we analyze the nature and phenomenology of the glass transition as a function of sequence correlations.
A. Irbäck, A. Montanari, E. I. Shakhnovich, J.-P. Bouchaud, J. D. Bryngelson, J. F. Nagle, M. Mézard, M. Mézard, M. Mézard, M. Müller, P. G. de Gennes, P. G. Wolynes, S. Lise, T. Garel, V. S. Pande   +14 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source