Results 81 to 90 of about 220,492 (303)

Elastic properties of Zr-based bulk metallic glasses studied by resonant ultrasound spectroscopy [PDF]

open access: yes
We report measurements of the elastic properties of Zr-based bulk metallic glasses, Zr52.5Cu17.9Ni14.6Al10Ti5, Zr50Cu30Ni10Al10, and Zr50Cu40Al10 between 5 K and 300 K.
Zhang, Zhiying   +4 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Glasses for Glass Electrode

open access: yesThe Journal of the Society of Chemical Industry, Japan, 1958
今日,pHの測定には,ほとんどガラス電極が使用されている現状であり,また,このガラス電極の進歩によって,更に,pH自動制御の可能性が生まれてきた。本研究ではガラス電極用ガラスの性能改良化を目的として,リチウム・ガラス(Li2O含量を26~28mol%に固定)の組成を系統的に変化させ,各ガラス成分のガラス電極特性に及ぼす影響を検討してみた。その結果,ZrO2,CeO2,Al2O3,V2O5,B2O3等の成分で,BaOを置換していくと,いずれもアルカリ誤差の大きくなることがわかった。また,アルカリ誤差の小さいガラスの組成は,SiO259~64mo1%,Li2O26~28mol%,La2O3+ BaO10~13mo1%であった。
Shinzo Okada   +2 more
openaire   +2 more sources

Clinopyroxene based glasses and glass-ceramics for functional applications [PDF]

open access: yes, 2009
Doutoramento em Ciência e Engenharia de MateriaisAs piroxenas são um vasto grupo de silicatos minerais encontrados em muitas rochas ígneas e metamórficas.
Goel, Ashutosh
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Quantum-Chemistry Study of the Hydrolysis Reaction Profile in Borate Networks: A Benchmark

open access: yesMolecules
This investigation involved an ab initio and Density Functional Theory (DFT) analysis of the hydrolysis mechanism and energetics in a borate network. The focus was on understanding how water molecules interact with and disrupt the borate network, an area
Francesco Muniz-Miranda   +4 more
doaj   +1 more source

Structural Characterisation of Bioactive Glasses [PDF]

open access: yes, 2007
Melt-quenched glasses containing SiO2, CaO, Na2O and P2O5, and sol-gel derived glasses containing SiO2 and CaO are known to have bioactive properties. Foaming of binary sol-gel derived bioactive glasses containing SiO2 and CaO can be used to produce ...
Fitzgerald, Victoria
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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