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GSH-Related Enzymes GPx4, Chac1, and GSTs and Redox Regulation of Ferroptosis in Cancer. [PDF]
Kalinina E.
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Potential mechanisms of traditional Chinese medicine in the treatment of liver cirrhosis: a focus on gut microbiota. [PDF]
Sun S, Zhang G, Lv S, Sun J.
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Early Growth and Serum Metabolic Profiling of One-Month-Old MSTN-Knockout Xinjiang Brown Cattle via CRISPR/Cas12Mix. [PDF]
Ma J +7 more
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X-ray and DFT Study of Glaucocalyxin A Compound with Cytotoxic Activity
The title compound glaucocalyxin A (1) (7, 14-dihydroxy-ent-kaur-16-en-3,15-dione) isolated from the leaves of isodon excisoides was characterized by IR, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, HMBC, and EIMS, and its crystal structure was determined by single-crystal X-ray diffraction. The X-ray crystal structure revealed that the molecular backbone of the
An-An Wu, Lan Ding
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Natural Product Research, 2014
Glaucocalyxin A is a natural ent-Kaurane diterpenoid. It has been widely studied for some important biological activities like cytotoxicity and anti-tumour, anti-bacterial, anti-oxidative, anti-coagulative, anti-thrombotic, immune and anti-neuroinflammatory activities.
Yong-Sheng Jin
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Glaucocalyxin A is a natural ent-Kaurane diterpenoid. It has been widely studied for some important biological activities like cytotoxicity and anti-tumour, anti-bacterial, anti-oxidative, anti-coagulative, anti-thrombotic, immune and anti-neuroinflammatory activities.
Yong-Sheng Jin
exaly +3 more sources
Glycosylation of Glaucocalyxin a and Evaluation of Its Cytotoxic Activity
Chemistry of Natural Compounds, 2020The 7,14-diglucoside of glaucocalyxin A was prepared by a five-step reaction. Its structure was confirmed by spectroscopic methods, and its cytotoxic activity was tested by the MTT method.
Yong-Sheng Jin
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Synthesis and Cytotoxic Activity of Hydroxy-Substituted Glaucocalyxin A
Pharmaceutical Chemistry Journal, 2019Six new glaucocalyxin A derivatives were synthesized by hydroxy substitution, their structures were elucidated on the basis of spectral analysis, and cytotoxic activity was tested by MTT method. Not all of the obtained glaucocalyxin A derivatives have their cytotoxicity enhanced as a result of this substitution.
Xu-Xu Zheng
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