Results 101 to 110 of about 470,158 (371)

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

open access: yesAdvanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv   +11 more
wiley   +1 more source

Tobacco and Intra Ocular Pressure [PDF]

open access: yes, 2002
Glaucoma is an optic nerve disorder caused by raised intraocular pressure. Among many drugs and agents causing glaucoma, tobacco has been found to be one of the important agents.
Ilanthody, Dr Kishore Krishna
core   +1 more source

Is “normal tension glaucoma” glaucoma?

open access: yesMedical Hypotheses, 2019
Primary open angle glaucoma (POAG) represents a distinct disease entity with elevated intraocular pressure (IOP) as the main risk factor, even though the reasons for why the IOP is elevated remains to be elucidated. It is considered that normal tension glaucoma (NTG) is a subtype of POAG, comprising a special form of glaucomatous neurodegeneration or ...
Xuyang Liu, Ning Fan, Junkai Tan
openaire   +3 more sources

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

open access: yesAdvanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz   +4 more
wiley   +1 more source

Minimally-invasive glaucoma surgeries (MIGS) for open angle glaucoma: A systematic review and meta-analysis

open access: yesPLoS ONE, 2017
Background MIGS have been developed as a surgical alternative for glaucomatous patients. Purpose To analyze the change in intraocular pressure (IOP) and glaucoma medications using different MIGS devices (Trabectome, iStent, Excimer Laser Trabeculotomy ...
Carlo Lavia   +4 more
semanticscholar   +1 more source

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

open access: yesAdvanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu   +13 more
wiley   +1 more source

Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort

open access: yesBMC Research Notes, 2018
Objective Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye.
Altaf A. Kondkar   +5 more
doaj   +1 more source

Age effect on retina and optic disc normal values [PDF]

open access: yes, 2005
Purpose: To investigate retinal thickness and optic disc parameters by the Retinal Thickness Analyzer (RTA) glaucoma program in older normal subjects and to determine any age effect.
Aljoscha S. Neubauer   +24 more
core   +1 more source

Glaucoma [PDF]

open access: yes, 2007
Glaucoma is a chronic neurodegenerative disease of the optic nerve, in which apoptosis of retinal ganglion cells (RGCs) and progressive loss of optic nerve axons result in structural and functional deficits in glaucoma patients. This neurodegenerative disease is indeed a leading cause of blindness in the world.
Gülgün, Tezel, Martin B, Wax
openaire   +2 more sources

A deep learning model for the detection of both advanced and early glaucoma using fundus photography

open access: yesPLoS ONE, 2018
Purpose To build a deep learning model to diagnose glaucoma using fundus photography. Design Cross sectional case study Subjects, Participants and Controls: A total of 1,542 photos (786 normal controls, 467 advanced glaucoma and 289 early glaucoma ...
Jin Mo Ahn   +5 more
semanticscholar   +1 more source

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