Results 71 to 80 of about 464,611 (330)

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets. [PDF]

, 2018
PurposeTo validate the prediction accuracy of variational Bayes linear regression (VBLR) with two datasets external to the training dataset.MethodThe training dataset consisted of 7268 eyes of 4278 subjects from the University of Tokyo Hospital.
Asaoka, Ryo, Fujino, Yuri, Hirasawa, Kazunori, Kashiwagi, Kenji, Matsuura, Masato, Miki, Atsuya, Mizoue, Shiro, Mori, Kazuhiko, Murata, Hiroshi, Shoji, Nobuyuki, Suzuki, Katsuyoshi, Tanito, Masaki, Yamashita, Takehiro, Zangwill, Linda M   +13 more
core   +1 more source

Ocular Findings as the Most Striking Manifestation of a SMAD3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Loeys‐Dietz syndrome (LDS) is a heritable connective tissue disorder with variable expressivity. It is a multisystemic condition mainly characterized by a propensity for arterial aneurysms and dissections, skeletal manifestations, hypertelorism, bifid uvula, craniosynostosis, and cutaneous features.
Noémie Villeneuve‐Cloutier, Christie A Boswell‐Patterson, Lucas Bronicki, Krista M. Vincent, Kalin Wilk, Andrea C. Yu, Gail E. Graham, Julie Richer   +7 more
wiley   +1 more source

Glaucoma - the significant challenge for the healthcare system in Poland

Journal of Education, Health and Sport, 2022
Introduction Glaucoma is a group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells (RGCs) and visual field loss. Glaucoma is the leading cause of irreversible blindness in the world.
Natalia Osial, Agnieszka Kaczyńska, Adrianna Gorecka, Piotr Stępień, Dorota Pożarowska, Tomasz Żarnowski   +5 more
doaj   +1 more source

Effects of glaucoma and snoring on cerebral oxygenation in the visual cortex: a study using functional Near Infrared Spectroscopy (fNIRS) [PDF]

, 2018
Purpose: The purpose of this study was to investigate the effects of snoring and glaucoma on the visual Haemodynamic Response (HDR) using functional Near Infrared Spectroscopy (fNIRS).
Aitchison, Ross T., Hill, Gemma, Imrie, Jayne, Kennedy, Graeme J., Mansfield, David, Morrison, Gordon, Shahani, Uma, Simmers, Anita J., Ward, Laura M.   +8 more
core   +1 more source

A Novel Pathogenic Variant in CRB1 as the Cause of Non‐Syndromic Retinitis Pigmentosa in a Geographical Isolate in Northern Italy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Non‐syndromic Retinitis Pigmentosa (NsRP) was well known as one of the causes of visual impairment already in the 19th century. Giuseppe Albertotti, Professor of Ophthalmology at the University of Modena (Italy) in 1893, described a high prevalence of NsRP in a geographic isolate, the small village of Colloro, in northwestern Italy.
Andrea Guala, Fabio Sirchia, Claudia Scotti, Elena Rossi, Roberta Falcioni, Silvano Ragozza, Antonella Casella, Enza Maria Valente, Cesare Danesino   +8 more
wiley   +1 more source

Contemporary Approach to Narrow Angles

Journal of Ophthalmic & Vision Research
Glaucoma is the leading cause of irreversible blindness worldwide. Among all glaucoma types, primary angle closure glaucoma (PACG) affects approximately 23 million people worldwide, and is responsible for 50% of glaucoma-related blindness, highlighting ...
Wesam Shamseldin Shalaby, Rohit Reddy, Reza Razeghinejad, L. Jay Katz   +3 more
doaj   +1 more source

Construction of miRNA-mRNA regulatory network indicates potential biomarkers for primary open-angle glaucoma

BMC Medical Genomics, 2023
Background Trabecular meshwork (TM) dysfunction-induced elevation of intraocular pressure has been identified as the main risk factor of irreversible optic nerve injury in Primary open‑angle glaucoma (POAG).
Xiaoyu Zhou, Feng Zhang, Xinyue Zhang, Dengming Zhou, Yang Zhao, Baihua Chen, Xuanchu Duan   +6 more
doaj   +1 more source

Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study. [PDF]

, 2018
The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients.
Galli, Fabio, Hollander, Lital, Italian Study Group on QoL in Glaucoma, Katsanos, Andreas, Oddone, Francesco, Poli, Davide, Quaranta, Luciano, Riva, Ivano, Rulli, Eliana, Torri, Valter, Weinreb, Robert N   +10 more
core   +2 more sources

Recurrence Risk in Pediatric Noninfectious Uveitis During Adalimumab Tapering: An International Multicenter Retrospective Study

Arthritis &Rheumatology, EarlyView.
Objective This study aims to assess the risk of noninfectious uveitis (NIU) relapse in pediatric patients undergoing adalimumab (ADA) tapering, evaluating potential predictors of such risk. Methods We conducted a multicenter retrospective cohort study involving pediatric patients with NIU who underwent ADA tapering due to inactive uveitis.
Achille Marino, Maria Vittoria Cicinelli, Elisabetta Miserocchi, Stefania Costi, Francesco Baldo, Maurizio Virgilio Gattinara, Pierluigi Scandale, Scott D. Smith, Debra A. Goldstein, Dina Baddar, Terese K. A. Gerges, Timothy M. Janetos, Matilde Ruiz‐Cruz, Kazuichi Maruyama, Massimiliano Serafino, Paola Camicione, Vishali Gupta, Radgonde Amer, Emilio M. Dodds, Sebastian Inchauspe, Marion R. Munk, Ester Carreño, Soon‐Phaik Chee, Aniruddha Agarwal, Ariel Schlaen, Ramiro A. Gómez, Cristobal A. Couto, Moncef Khairallah, Piergiorgio Neri, Cecilia B. Chighizola, Roberto F. Caporali, Francesco Pichi   +31 more
wiley   +1 more source

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

Nature Genetics, 2018
Glaucoma is the leading cause of irreversible blindness globally1. Despite its gravity, the disease is frequently undiagnosed in the community2. Raised intraocular pressure (IOP) is the most important risk factor for primary open-angle glaucoma (POAG)3,4.
A. Khawaja, J. C. Cooke Bailey, N. Wareham, R. Scott, Mark J. Simcoe, R. Igo, Yeunjoo E. Song, R. Wojciechowski, Ching-Yu Cheng, P. Khaw, L. Pasquale, J. Haines, P. Foster, J. Wiggs, C. Hammond, P. Hysi   +15 more
semanticscholar   +1 more source