Results 121 to 130 of about 1,591,834 (257)

Modulation of Anaphase‐Promoting Complex Genes Regulates Root‐Knot Nematode Gall Development and Plant Susceptibility

Plant, Cell &Environment, EarlyView.
ABSTRACT The anaphase‐promoting complex/cyclosome (APC/C) is a multi‐subunit E3 ubiquitin ligase that regulates cell cycle progression, but its role in plant‐pathogen interactions is poorly understood. Here, we demonstrate that regulation of the ubiquitin–proteasome system, involving APC/C‐associated components, is critical for coordinating host cell ...
Aline Köhn Carneiro, Kércya Maria Simões de Siqueira, La Hoang Anh, Sophie Pagnotta, Danila Cabral do Nascimento, Nubia Barbosa Eloy, Harald Keller, Adriana Silva Hemerly, Janice de Almeida Engler   +8 more
wiley   +1 more source

The Orphans of Bishop Richard Fletcher: New Archival Discoveries on the Siblings of Playwright John Fletcher

Renaissance Studies, EarlyView.
ABSTRACT This article presents new archival discoveries concerning the siblings of early modern playwright John Fletcher following the sudden death of their father, Richard Fletcher, Bishop of London, in 1596. Navigating the epistemological limits of adversarial legal records from Chancery and the Star Chamber, the study reveals the tumultuous ...
Domenico Lovascio
wiley   +1 more source

Patients characteristics and subgroup analysis according to biopsy Gleason score.

, 2016
Patients characteristics and subgroup analysis according to biopsy Gleason score.
Jong Jin Oh (610306), Young Ik Lee (605887), Hak Min Lee (414681), Sung Kyu Hong (423172), Sangchul Lee (423170), Sang Eun Lee (123924), Seok-Soo Byun (423173), Jung Ki Jo (2157004)   +7 more
core   +1 more source

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah, Mohanad Sameer Jabbar, Saif H. Alwaeli, Noor Ayesha, Mohamed Babiker A. Mohamed, Muhammad I. Khan   +5 more
wiley   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

ManyBabies 3: A Multi‐Lab Study of Infant Algebraic Rule Learning

Developmental Science, Volume 29, Issue 6, November 2026.
ABSTRACT The ability to learn and apply rules lies at the heart of cognition. In a seminal study, Marcus et al. (1999) reported that 7‐month‐old infants learned abstract rules over syllable sequences and were able to generalize those rules to novel syllable sequences.
Ingmar Visser, Andreea Geambasu, George Kachergis, Cátia M. Oliveira, Joscelin Rocha‐Hidalgo, Martin Zettersten, Teruni Ahamat, Nicolás Alessandroni, Nadja Althaus, Sudha Arunachalam, Suzanne Aussems, Emma L Axelsson, Zeynep Aydin, Heidi A. Baumgartner, Christina Bergmann, Roberta Bettoni, Alexis K. Black, Hermann Bulf, Krista Byers‐Heinlein, Chiara Capparini, Lily Carroll, Alexandra Carstensen, Rebekka Cebulla, Xiaoyun Chen, Kateřina Chládková, Benedetta Colavolpe, Rodica R Constantine, Elísabet Eir Cortes, Frances L. Doyle, Anna Exner, Samuel H Forbes, Laura Franchin, Alessandra Geraci, Judit Gervain, Nayeli Gonzalez‐Gomez, Silje Hagelund, Erin E Hannon, Naomi Havron, Sagi Jaffe‐Dax, Scott P Johnson, Wiktoria Jędryczka, Natalia Kartushina, Melissa Kline Struhl, Ada Koleini, Abhinav Kona, Shannon P Kong, Jessica E Kosie, Monika Kuc̆erová, Katerina Cook, Jared Wayne Leslie, Casey Lew‐Williams, Scarlet Wan Yee Li, Romi Livne, Ellen Marklund, Julien Mayor, Michal Misiak, David Moreau, Jutta L. Mueller, Amber Muhinyi, Alyssa A Quinn, Maartje E. J. Raijmakers, Audun Rosslund, Iris‐Corinna Schwarz, Jeanne L Shinskey, Mohinish Shukla, Sylvain Sirois, Piotr Sorokowski, Basma Sowan, Tibor Tauzin, Angeline Sin Mei Tsui, Martina Turconi, Rebeca C Urizar, Lisa Wagner, Stephanie Wermelinger, Gert Westermann, Ivonne Weyers, Luiza S. B. Yuan, Martina S. Zaharieva, Tania S. Zamuner, Barbara Zapiór, Simone Zasso, J. Grace Zhou, Melanie Soderstrom, Clara C. Levelt   +83 more
wiley   +1 more source

Dysregulated TIE‐2 expression in Alzheimer's disease: Further considerations on regional specificity and shedding evidence

Brain Pathology, EarlyView.
Shi‐qi Zhang, Meichen Liu
wiley   +1 more source

Requesting Diagnostic Imaging in Nurse Practitioner Practice: Results of a National Survey

Journal of Clinical Nursing, Volume 35, Issue 11, Page 4795-4805, November 2026.
ABSTRACT Aim To examine how nurse practitioners in Australia request diagnostic imaging and identify educational and system‐level barriers that influence this practice. Design Cross‐sectional national survey. Methods An online survey of nurse practitioners in Australia.
Mary Kearns, Patrick Brennan, Christopher Helms, Thomas Buckley   +3 more
wiley   +1 more source

Comparison of the Cox Proportional Hazards Model and Random Survival Forest Algorithm for Predicting Patient‐Specific Survival Probabilities in Clinical Trial Data

Biometrical Journal, Volume 68, Issue 5, October 2026.
ABSTRACT The Cox proportional hazards model is often used to analyze data from randomized controlled trials (RCTs) with time‐to‐event outcomes. Random survival forest (RSF) is a machine‐learning algorithm known for its high predictive performance. We conduct a comprehensive neutral comparison study to compare the performance of Cox regression and RSF ...
Ricarda Graf, Susan Todd, M. Fazil Baksh
wiley   +1 more source

Hyperpolarized MRI in Oncology—A Review of Clinical Studies and Evaluation of Preclinical Liver Studies

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Hyperpolarized MRI is a promising clinical imaging modality in oncology, offering at least nine imaging contrasts obtainable with hyperpolarized [1‐13C]pyruvate as the injected agent, depending on the tissue and condition under investigation. Preclinical studies suggest that hyperpolarized MRI is warranted for detecting hepatocellular carcinoma within ...
Naama Lev‐Cohain, Jacob Sosna, Rachel Katz‐Brull   +2 more
wiley   +1 more source