Results 21 to 30 of about 1,591,834 (257)

Korelasi Skor Gleason dengan Kadar Prostat Spesifik Antigen (PSA) Pada Pasien Karsinoma Prostat

Majalah Kedokteran Andalas, 2021
Prostatic carcinoma is malignancy of the prostate gland which is found in inferior portion of the bladder and anterior part of the rectum. To diagnose prostatic carcinoma, required Prostate Specific Antigen (PSA) levels and Gleason Score examination. PSA
Niniek Hardini
doaj   +1 more source

Lineage Relationship of Gleason Patterns in Gleason Score 7 Prostate Cancer [PDF]

Cancer Research, 2013
Abstract Gleason score 7 (GS7) prostate cancer [tumors with both Gleason patterns 3 (GP3) and 4 (GP4)] portends a significantly more aggressive tumor than Gleason score 6 (GS6). It is, therefore, critical to understand the molecular relationship of adjacent GP3 and GP4 tumor cell populations and relate molecular abnormalities to disease ...
Irina V, Kovtun, John C, Cheville, Stephen J, Murphy, Sarah H, Johnson, Shabnam, Zarei, Farhad, Kosari, William R, Sukov, R Jeffrey, Karnes, George, Vasmatzis   +8 more
openaire   +2 more sources

Gleason score and laterality concordance between prostate biopsy and prostatectomy specimens

International Brazilian Journal of Urology, 2009
Objectives: Prostate biopsy involvement and Gleason score guide treatment decisions in prostate cancer. We evaluated concordance in Gleason score and laterality between biopsy and radical retropubic prostatectomy (RRP) specimens and factors that ...
Kenneth G. Nepple, Terry L. Wahls, Stephen L. Hillis, Fadi N. Joudi   +3 more
doaj   +1 more source

Predicting Low-Risk Prostate Cancer from Transperineal Saturation Biopsies

Prostate Cancer, 2016
Introduction. To assess the performance of five previously described clinicopathological definitions of low-risk prostate cancer (PC). Materials and Methods. Men who underwent radical prostatectomy (RP) for clinical stage ≤T2, PSA
Pim J. van Leeuwen, Amila Siriwardana, Monique Roobol, Francis Ting, Daan Nieboer, James Thompson, Warick Delprado, Anne-Marie Haynes, Phillip Brenner, Phillip Stricker   +9 more
doaj   +1 more source

Correlation between Prostate Specific Antigen and Prostate Biopsy Gleason Score

Annals of Health Research, 2019
Background: Prostate Specific Antigen (PSA) is a commonly used marker in prostate cancer management. Gleason grading is one of the most powerful predictors of prostatic biological behaviour.
Ngwu PE, Achor GO, Eziefule VU, Alozie FT   +3 more
doaj   +1 more source

The Utilization of Gleason Grade as the Primary Criterion for Ordering Nuclear Bone Scan in Newly Diagnosed Prostate Cancer Patients

The Scientific World Journal, 2009
Utilization of nuclear bone scans for staging newly diagnosed prostate cancer has decreased dramatically due to PSA-driven stage migration. The current criteria for performing bone scans are based on limited historical data.
Chad W. M. Ritenour, John T. Abbott, Michael Goodman, Naomi Alazraki, Fray F. Marshall, Muta M. Issa   +5 more
doaj   +1 more source

Upgrading of gleason score on radical prostatectomy specimen compared to the pre-operative needle core biopsy: An Indian experience

Indian Journal of Urology, 2010
Objectives : To assess the accuracy of Gleason grading/scoring on preoperative needle core biopsy (NCB) compared to the radical prostatectomy (RP) specimen. Materials and Methods : Data of NCB and RP specimens was analyzed in 193 cases.
Rishi Nayyar, Prabhjot Singh, Narmada P Gupta, Ashok K Hemal, Prem N Dogra, Amlesh Seth, Rajeev Kumar   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Cribriform architecture in radical prostatectomies predicts oncological outcome in Gleason score 8 prostate cancer patients [PDF]

, 2020
The Gleason score is an important parameter for clinical outcome in prostate cancer patients. Gleason score 8 is a heterogeneous disease including Gleason score 3 + 5, 4 + 4, and 5 + 3 tumors, and encompasses a broad range of tumor growth patterns.
Pelger, R.C.M., Poel, H.G. (Henk) van der, Leenders, G.J.H.L. (Geert), Helleman, J. (Jozien), Verhoef, E.I. (Esther), Hollemans, E., Bekers, E., Pelger, R.C.M. (R. C M), Bekers, E.M. (Elise), Roobol-Bouts, M.J. (Monique), Bangma, C.H., Poel, H. van der, Bangma, C.H. (Chris), Osanto, S., Wezel, T. (Tom) van, Verhoef, E.I., Hollemans, E. (Eva), Helleman, J., Wezel, T. van, Osanto, S. (Susanne), Rietbergen, J.B. (John), Roobol, M.J., Leenders, G.J.L.H. van, Rietbergen, J.   +23 more
core   +4 more sources