Results 61 to 70 of about 1,591,834 (257)

Natural History of PI‐RADS 3 Lesions on Serial Prostate mpMRI

The Prostate, EarlyView.
ABSTRACT Objective PI‐RADS 3 lesions on prostate multiparametric MRI (mpMRI) are indeterminate findings with debated management. We evaluated their radiologic evolution on follow‐up mpMRI and correlated imaging changes with biopsy outcomes. Methods We retrospectively identified 166 men with at least one PI‐RADS 3 lesion on initial mpMRI and at least ...
Tomer Bashi, Yanai Rubinstein, Adi Kidron, Ron Marom, Yuval Rand, Meitar Atias, Sophie Barnes, Ibrahim Fahoum, Gal Keren‐Paz, Mario Sofer, Ofer Yossepowitch, Snir Dekalo, Avi Beri, Roy Mano   +13 more
wiley   +1 more source

Differentiation of prostate cancer lesions with high and with low Gleason score by diffusion-weighted MRI. [PDF]

, 2017
OBJECTIVES To differentiate prostate cancer lesions with high and with low Gleason score by diffusion-weighted-MRI (DW-MRI). METHODS This prospective study was approved by the responsible ethics committee. DW-MRI of 84 consenting prostate and/or
Boxler, Silvan, Thöny, Harriet C., Barbieri, Sebastiano, Brönnimann, Michael, Vermathen, Peter   +4 more
core   +2 more sources

Prognostic Value of Gleason Score for Overall Survival in Prostate Cancer: A Population-Based SEER Cohort Study

Onco
Background/Objectives: Prostate cancer is biologically heterogeneous, and prognostic stratification informs the choice between definitive treatment and conservative management.
Onyekachi Anya, Ogbonna Chikere, Progress Asoluka, Oluchi Idenyi, Alexandra O. Sokolova   +4 more
doaj   +1 more source

Insulin‐Like Growth Factor Axis and Survival in Metastatic Hormone‐Sensitive Prostate Cancer: Post‐Hoc Analysis From the ENZAMET Phase 3 Trial

The Prostate, EarlyView.
ABSTRACT Background A higher ratio of IGF‐1:IGF binding protein 1 (IGFBP1) was associated with improved prognosis in the CHAARTED trial of docetaxel in participants with metastatic hormone‐sensitive prostate cancer (mHSPC). The ENZAMET trial demonstrated the survival benefit of adding enzalutamide to androgen deprivation therapy (ADT) in mHSPC, and ...
Michael A. Cilento, Hui‐Ming Lin, Nicole Yeung, Rachel M.N. Kim, Neil Portman, Martin R. Stockler, Andrew J. Martin, Vinod Subhash, Sonia Yip, Lisa M. Butler, Ian C. Marschner, Peter J. Meikle, Arun A. Azad, Ian D. Davis, Lisa G. Horvath, Christopher J. Sweeney   +15 more
wiley   +1 more source

Gleason score correlation with SEPT9_i1 staining intensity.

, 2015
Mean SEPT9_i1 staining intensity ± SE of each Gleason score group (score 5: 3 patients, score 6: 8 patients, score 7: 19 patients, score 8: 3 patients, score 9: 6 patients and score 10: 2 patients) was calculated using either visual scoring (A) or ...
Roni Gilad (727843), Larissa German (727844), Eli Pikarsky (103960), Nicola J. Mabjeesh (447321), Ilan Stein (131429), Karen Meir (258188)   +5 more
core   +1 more source

Relación entre score Gleason biópsico y score Gleason tras prostatectomía radical en pacientes sometidos a biopsia sextante vs 12 cilindros [PDF]

, 2010
Objetivo: El cáncer de próstata es una patología cada vez más prevalente por la longevidad de la población. Es por ello que cada vez con más frecuencia se somete a los pacientes a realización de biopsia prostática para realizar su diagnóstico de certeza.
López-Carmona Pintado,Fernando, Valle-Díaz de la Guardia,Francisco, López-León,Víctor Manuel, Arrabal-Polo,Miguel Ángel, Mijan-Ortiz,José Luis, Arrabal-Martín,Miguel, Tinaut-Ranera,Javier, Zuluaga-Gómez,Armando, Jiménez-Pacheco,Antonio, Merino-Salas,Sergio   +9 more
core   +1 more source

Prognostic Value of MRI‐Derived Apparent Diffusion Coefficient in Intermediate‐Risk Prostate Cancer Treated With Definitive Radiotherapy

The Prostate, EarlyView.
ABSTRACT Background Intermediate‐risk prostate cancer (IR‐PCa) is a heterogeneous disease with variable clinical outcomes despite established risk classification. We evaluated whether pretreatment tumor apparent diffusion coefficient (ADC) derived from multiparametric MRI was associated with long‐term outcomes and provided additional prognostic ...
Cem Onal, Gurcan Erbay, Aysenur Elmali, Birhan Demirhan, Ozan Cem Guler   +4 more
wiley   +1 more source

Correlation between biomarker and Gleason score.

, 2019
Bars show Healthy patients against Gleason score breakdown. STEAP1, 2, 4 and DMT1 protein expression was significantly increased in PCa samples compared to healthy samples.
Stephanie E. A. Burnell (7164608), Suzie Howarth (7164614), Claire Morgan (333434), Shareen H. Doak (7164620), Howard Kynaston (7164617), Samantha Spencer-Harty (7164611), Owen Bodger (338917)   +6 more
core   +1 more source

The impact of biopsy core length on the discrepancy in Gleason scores between biopsy and radical prostatectomy specimen

BJUI Compass
Objective To assess the impact of the biopsy core length on the discrepancy in Gleason score between biopsy and radical prostatectomy specimens. Patients and Methods Retrospective analysis of clinical data from 247 patients who underwent transperineal ...
Cheng‐hao Guo, Yin‐shuai Geng, Liang‐yong Zhu, Xue‐fei Ding, Yang Luan   +4 more
doaj   +1 more source

Comparison of Gene Enrichment Between Prostate Tissue and Urine for Non‐Invasive Biomarker Development

The Prostate, EarlyView.
ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing, Minqi Xu, Dan Dion, Vanessa F. Bratti, Ania A. Namin, D. Robert Siemens, Palak G. Patel, Robert J. Gooding, Jane Bayani, Hamid Ghaedi, Anna Y. Lee, David M. Berman   +11 more
wiley   +1 more source