Results 141 to 150 of about 3,631,478 (254)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Bilateral Orbital Fat Hyperintensity in Early Glial Fibrillary Acidic Protein Astrocytopathy: A Case Report. [PDF]

Neurol Neuroimmunol Neuroinflamm
Ito Y, Ohyama K, Kimura A, Yamashita K, Nakayabu M, Fukami Y, Shimohata T, Katsuno M.   +7 more
europepmc   +1 more source

GLIAL FIBRILLARY ACIDIC PROTEIN SEBAGAI PREDIKTOR KEMATIAN CIDERA KEPALA

, 2013
The incidence of head injury due to trauma increases the morbidity and mortality is relatively high, thus requiring a fast and precise handling to get a good clinical output.
, dr. Usi Sukorini, M.Kes, Sp.PK-K, , Wahid Syamsul Hadi   +1 more
core  

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Clinical utility of measuring circulating glial fibrillary acidic protein in severe stroke. [PDF]

Stroke Vasc Neurol
Gjordeni M, Pansell J, Thelin EP, Mazya MV, Pourhamidi K, Lindsberg PJ, Mattila OS, Cooray C.   +7 more
europepmc   +1 more source

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP)

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP) is a rare condition associated with the presence of antibodies against an intermediate protein located between the finer microfilaments and the larger microtubules in astrocytes.
S. A. Dzhukkaeva, O. N. Voskresenskaya, I. Yu. Oganesyan, Sh. R. Nabiev   +3 more
core   +1 more source

Bioengineered microbiotic levodopa therapy improves cognition and reduces pathology in a rat model of Alzheimer's disease

British Journal of Pharmacology, EarlyView.
Background and Purpose Degeneration of the pontine noradrenergic and midbrain dopaminergic systems contributes to cognitive‐behavioural disturbances during the prodromal stages of Alzheimer's disease (AD). We developed a genetically engineered, programmable probiotic Escherichia coli Nissle 1917 strain (EcNrhaL‐DOPA) capable of producing L‐3,4 ...
Mona Abdelhamid, Piyush Padhi, Mahsa Gifani, John S. Beck, Jacob P. Thomas, Gargi Khadse, Catherine Kudela, Gregory J. Phillips, Anumantha G. Kanthasamy, Scott E. Counts   +9 more
wiley   +1 more source

Characteristics and prognostic factors of cognitive impairment in autoimmune glial fibrillary acidic protein astrocytopathy. [PDF]

J Neurol
Mori Y, Takekoshi A, Ono Y, Yoshikura N, Shimohata T, Kimura A.   +5 more
europepmc   +1 more source

Kcnv2 E151X Mouse Captures Hallmarks of KCNV2‐Associated Retinal Dystrophy

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background KCNV2‐associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor behaviour and progressive deterioration of vision. Patients have characteristic electroretinography abnormalities, including reduced cone response, delayed and reduced rod response to low light ...
Nermina Xhaferri, Sumit Biswas, Benjamin Davies, Moritz Lindner   +3 more
wiley   +1 more source

Severe chronic neutrophilic cholangiohepatitis with massive choledocholithiasis and hepatolithiasis in a pony

Equine Veterinary Education, EarlyView.
Summary A 20‐year‐old Camargue pony mare was referred for acute‐onset neurological signs and intermittent colic. Clinical examination revealed obtundation, cranial nerve deficits, head pressing, ventral strabismus and ataxia. Laboratory analyses showed marked hyperammonaemia, hyperbilirubinemia, severe increases in liver enzymes, hypoalbuminaemia and ...
C. Maino, N. Ellero, M. Morini, L. V. Muscatello, S. Sabattini, G. Bettini   +5 more
wiley   +1 more source