Results 181 to 190 of about 3,631,478 (254)

Diagnostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in Differentiating Primary From Serious Secondary Headache. [PDF]

Eur J Neurol
Camerin SJ, Atila C, Blum CA, Sandgren S, Maleska A, Papadopoulou A, Kuhle J, Katan M, Christ-Crain M.   +8 more
europepmc   +1 more source

Elevated endogenous glucagon‐like peptide‐1 as a novel Alzheimer's disease biomarker associated with neuroinflammation and Aβ pathology

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Alzheimer's disease (AD), a neurodegenerative disorder, is pathologically defined by the accumulation of amyloid‐β (Aβ) plaques, hyperphosphorylated tau tangles and sustained neuroinflammation. Glucagon‐like peptide‐1 (GLP‐1), originally characterised as an incretin hormone, is also expressed endogenously in the brain.
Jianping Li, Chenhui Ji, Jintao Wang, Jinwen Xiao, Haixia Li, Xinyi Xie, Nan Zhi, Yaying Song, Wenwei Cao, Liling Wang, Jieli Geng, Rujing Ren, Gang Wang   +12 more
wiley   +1 more source

Case Report: Efficacy of efgartigimod for autonomic dysfunction in patients with autoimmune glial fibrillary acidic protein astrocytopathy: a case series of 3 patients. [PDF]

Front Immunol
Ma H, Xie B, Wu Y, Zhou H, Ma F, Huang C, Zheng X.   +6 more
europepmc   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3542-3549, October 2026.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti, Felipe Vanz, Karina Giacomini Varela, Viviane Glaser, Diego de Carvalho, Aline Pertile Remor   +5 more
wiley   +1 more source

Glial Fibrillary Acidic Protein and Neurofilament Light Reference Intervals in Healthy Individuals.

JAMA Netw Open
Rousset RZ, Honey MIJ, den Braber A, van der Flier WM, Holstege H, Lorenz L, Wessels MHJ, Killestein J, Huisman M, Kok A, Beekman M, Slagboom PE, Ligthart L, de Geus E, Verberk IMW, Vermunt L, Teunissen CE.   +16 more
europepmc   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Mimicking Wernicke's Encephalopathy. [PDF]

Intern Med
Murakami K, Yorozu S, Eimoto T, Miyamoto K.   +3 more
europepmc   +1 more source

Microplastics as Emerging Neurotoxins: Brain Accumulation, Neuroinflammation, and Neurodegeneration Risk

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Microplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Alfi Sophian, Asmariani, Erika Ismayani
wiley   +1 more source

Autoimmune glial fibrillary acidic protein astrocytopathy mimicking acute ischemic stroke: a case report. [PDF]

Front Immunol
Hou X, Mo X, Chen T, Qin K, Yu S.
europepmc   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Serum GFAP and Age Accurately Distinguish AQP4‐IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

European Journal of Neurology, Volume 33, Issue 10, October 2026.
After a recent NMOSD attack, serum GFAP and age together provide a simple and powerful way to distinguish AQP4‐IgG NMOSD from MOGAD and related disorders. In 240 patients evaluated within 90 days of an attack from a 640‐patient cohort, this combination achieved high diagnostic accuracy (AUC up to 0.95).
Manon Rival, Fabien Rollot, Sabine Laurent‐Chabalier, Romain Casey, Illiasse El Bahi, Guillaume Brocard, Romain Marignier, Sophie Trouillet‐Assant, Sandra Vukusic, Agnès Fromont, David Axel Laplaud, Guillaume Mathey, Elisabeth Maillart, Laure Michel, Aurélie Ruet, Pierre Labauge, Xavier Ayrignac, Hélène Zephir, Jonathan Ciron, Jérôme de Sèze, Arnaud Kwiatkowski, Caroline Papeix, Pierre Branger, Christine Lebrun‐Frenay, Eric Berger, Pierre Clavelou, Olivier Heinzlef, Jean Pelletier, Abdullatif Al‐Khedr, Olivier Casez, Bertrand Bourre, Alain Créange, Thomas David, Laurent Magy, Jean‐Philippe Camdessanche, Inès Doghri, Amélie Dos Santos, Thibault Mura, Hanane Agherbi, Eric Thouvenot, for the OFSEP Group and NOMADMUS Investigators, Nicolas Collongues, Céline Cognet, Mireille Desille‐Dugast, Nathalie Dufay, Mathilde Berthome, Michael Hisbergues, Sylvain Lehmann, Laurence Liang, Céline Loiseau, Julie Marechal, Estelle Nisse, Françoise Durand‐Dubief, François Cotton, Bertrand Audoin, Mikael Cohen, Nicolas Collongues, Romain Deschamps   +57 more
wiley   +1 more source