Results 291 to 300 of about 118,654 (350)

Glial Fibrillary Acidic Protein in Brain Tumors

Oncology, 1986
Glial fibrillary acidic protein has been widely used in neurobiology and neuropathology as a specific marker for normal and abnormal astrocytes. Here, we report the immunostaining of 107 brain tumors and controls using an antiserum against glial fibrillary acidic protein. Selection of astroglia-derived tumors was easy and of high accuracy.
E, Luevano, M, Tena, A, Zamora, J, Sotelo   +3 more
openaire   +2 more sources

Glial fibrillary acidic protein antibody-positive meningoencephalomyelitis

Practical Neurology, 2018
Glial fibrillary acidic protein antibody-positive meningoencephalomyelitis is a newly described, possibly under-recognised, severe inflammatory condition of the nervous system. The clinical presentation is variable but most commonly is a combination of meningitis, encephalitis and myelitis; other manifestations may include seizures, psychiatric ...
Angeliki Zarkali, Oliver Cousins, D. Athauda, S. Moses, N. Moran, S. Harikrishnan   +5 more
semanticscholar   +4 more sources

An ELISA for glial fibrillary acidic protein

Journal of Immunological Methods, 2004
Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein of the astrocyte, and body fluid levels of GFAP are an important tool for estimating astrogliosis and astrocytic activation in vivo. This paper presents a new sandwich ELISA allowing quantification of GFAP(SMI26) from the cerebrospinal fluid (CSF).
A, Petzold, G, Keir, A J E, Green, G, Giovannoni, E J, Thompson   +4 more
openaire   +2 more sources

Glial fibrillary acidic protein and cartilage

Acta Neuropathologica, 1989
The presence of glial fibrillary acidic protein was tested for in cartilage of bronchi, trachea, pulmonary hamartomas, articular cartilage and chondrosarcomas. The cytoplasm of most chondrocytes in bronchi stained strongly positive, whilst in hamartomas only small foci at the edges reacted. Staining in the trachea was weak.
openaire   +2 more sources

Glial fibrillary acidic protein and Alzheimer's disease

Neurochemical Research, 1985
A major protein associated with Alzheimer's disease (AD) was detected by an electrophoretic study of temporal cortex obtained at autopsy from patients affected with AD, non-AD dementia, and normal controls matched for age and sex. A markedly increased amount of a 50,000 dalton molecular weight protein, which has been identified as glial fibrillary ...
S S, Panter, J D, McSwigan, J R, Sheppard, C R, Emory, W H, Frey   +4 more
openaire   +2 more sources

Case 309: Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

Radiology, 2023
A 64-year-old man presented with a 6-month history of lightheadedness and intermittent balance and coordination difficulties. Two months before admission, symptoms became more substantial and persistent, with a worsening sense of disequilibrium and unsteady gait. He reported difficulties pronouncing words and mild word-finding difficulties.
Paulo Puac-Polanco, Nader Zakhari, Gerard H. Jansen, Carlos Torres   +3 more
openaire   +2 more sources

Measurement of Glial Fibrillary Acidic Protein

Current Protocols in Toxicology, 2002
AbstractToxicant‐induced injury of the adult or developing central nervous system results in hypertrophy of astrocytes at the site of injury. The hallmark of this response is enhanced expression of the major intermediate filament protein of astrocytes, glial fibrillary acid protein (GFAP).
openaire   +2 more sources

Glial Fibrillary Acidic Protein in Tuberous Sclerosis

Psychiatry and Clinical Neurosciences, 1983
Abstract: We examined two cases of tuberous sclerosis for the presence of glial fibrillary acidic protein (GFAP) using the immunoperoxidase technique. The majority of abnormal giant cells in the cerebral cortex showed no reaction to anti‐GFAP. Some abnormal cells in the cortical tuber and white matter showed a weak positive reaction.
M, Tobo, Y, Mitsuyama, T, Kaku
openaire   +2 more sources

GLIAL FIBRILLARY ACIDIC PROTEIN IN HUMAN GLIOMAS

Neuropathology and Applied Neurobiology, 1978
The presence of GFA protein, an astrocyte specific antigen, was investigated in surgical biopsies of ninety‐five gliomas using an immunoperoxidase detection method. In some cases electron microscopy was added and also in one tumour immunoelectron microscopy. The results were correlated with the histological classification and grading of the tumours. In
VANDERMEULEN, JDM, HOUTHOFF, HJ, EBELS, EJ   +2 more
openaire   +3 more sources

Glial Fibrillary Acidic Protein in Serum is Increased in Alzheimer’s Disease and Correlates with Cognitive Impairment

Journal of Alzheimer's Disease, 2018
Reliable blood biomarkers for Alzheimer’s disease (AD) are missing. We measured astroglial GFAP in patients with AD (n = 28), frontotemporal dementia (bvFTD, n = 35), Parkinson’s disease (n = 11), Lewy body dementias (n = 19), and controls (n = 34 ...
P. Oeckl, S. Halbgebauer, S. Anderl-Straub, P. Steinacker, A. Huss, H. Neugebauer, C. V. von Arnim, J. Diehl-Schmid, T. Grimmer, J. Kornhuber, P. Lewczuk, A. Danek, A. Ludolph, M. Otto   +13 more
semanticscholar   +1 more source