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Cell-free synthesis of glial fibrillary acidic protein

Neurochemical Research, 1980
Glial fibrillary acidic (GFA) protein has been synthesized in an RNA-dependent cell-free system derived from rabbit reticulocytes. The cell-free synthesized product appears to have the same size as GFA protein isolated from bovine spinal cord, thus showing that GFA protein does not undergo detectable proteolytic processing.
P, Béguin, E M, Shooter, L F, Eng
openaire   +2 more sources

Dynamics of bovine glial fibrillary acidic protein phosphorylation

Neuroscience Letters, 1996
Recently, the dynamic features of the intermediate filaments (IF) have been revealed. The effect of phosphorylation on the dynamics of bovine glial fibrillary acidic protein (GFAP), the astroglial IF, was studied in vitro with fluorescently labeled GFAP.
Y, Nakamura, M, Takeda, T, Nishimura
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Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

Neurology India, 2023
Yuxin, Deng, Mingguo, Xie, Lichuan, Zeng
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Phosphorylation of the glial fibrillary acidic protein

Journal of Neuroscience Research, 1990
AbstractThe glial fibrillary acidic protein (GFAP) was found to be phosphorylated in vivo after intracerebral injection of [32P]‐orthophosphate, in brain Slices, and in a cell free system. The phosphorylated proteins were separated by two‐dimensional gel electrophoresis and then transferred to nitrocellulose sheets.
openaire   +2 more sources

Prognostic Value of Glial Fibrillary Acidic Protein in Patients With Moderate and Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis

Critical Care Medicine, 2019
Objectives: Biomarkers have been suggested as potential prognostic predictors following a moderate or severe traumatic brain injury but their prognostic accuracy is still uncertain.
Michèle Shemilt   +13 more
semanticscholar   +1 more source

Glial Fibrillary Acid Protein in Medulloblastomas

1983
Glial Fibrillary Acid Protein (GFAP) is regarded as an astroglial-specific component and its presence can therefore be used to control the degree of differentiation of glial elements (BIGNAMI and DAHL, 1974; 1977). This method is being used with increasing frequency in neuro-oncology, with some contradictory results, however (for review see De ARMOND ...
E. Schindler, F. Gullotta
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Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity

Expert Opinion on Drug Safety, 2005
A variety of '-omic' technologies are being increasingly applied in preclinical safety assessments. Such approaches, however, have not been implemented in neurotoxicity safety evaluations. Current regulatory guidelines for assessing neurotoxicity emphasise reliance on traditional histopathological stains and behavioural testing batteries.
James P, O'Callaghan, Krishnan, Sriram
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Glial Fibrillary Acidic Protein in Hepatic Encephalopathy

Journal of Neuropathology & Experimental Neurology, 1981
Basal ganglia, thalamus, cerebral cortex, and subcortical white matter were studied in ten cases of hepatic encephalopathy (HE), including three cases of acquired hepatocerebral degeneration (HCD), and in thirteen age-matched controls using the peroxidase-antiperoxidase immunohistochemical staining technique for glial fibrillary acidic (GFA) protein ...
R A, Sobel   +3 more
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Optic Disc Edema in Glial Fibrillary Acidic Protein Autoantibody–Positive Meningoencephalitis

Journal of neuro-ophthalmology, 2017
Background: Glial fibrillary acidic protein (GFAP) autoantibody–positive meningoencephalitis is a newly described entity characterized by a corticosteroid-responsive meningoencephalomyelitis.
John J. Chen   +7 more
semanticscholar   +1 more source

Autoimmune encephalitis in glial fibrillary acidic protein astrocytopathy

BMJ Case Reports
Autoimmune encephalitis due to glial fibrillar acidic protein (GFAP) astrocytopathy is a rare cause of subacute neuropsychiatric changes. In this case, a young patient presented with a viral prodrome and meningismus, followed by progressive encephalopathy and movement disorders over the span of 2 weeks.
Charlie Weige Zhao   +3 more
openaire   +2 more sources

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