Results 71 to 80 of about 2,551 (122)

Solvent effects, chemical reactivity, docking and antimicrobial activity of silver and gold nanocages glimepiride: Experimental and theoretical calculations

Chemical Physics Impact
Glimepiride, a sulonylurea, is employed to treat type 2 diabetes. This activity discusses the indications, mode of action, and precautions of glimepiride as type 2 diabetes treatments. In this study, we investigated the loading of Glimepiride onto Silver
G. Venkatesh, P. Vennila, S Balasubramaniyan   +2 more
doaj   +1 more source

Semaglutide Injection Once‐Weekly for Weight Management in Adults: Results From A Randomized Phase III, Active‐Controlled Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8602-8612, September 2026.
ABSTRACT Aim To evaluate and compare the efficacy, safety, and immunogenicity of a synthetic semaglutide injection (Test semaglutide) with Wegovy (Reference semaglutide) injection for weight management. Materials and Methods This randomized, Phase III, non‐inferiority study included adults with obesity or overweight with or without comorbidities from ...
Unnikrishnan Ambika Gopalakrishnan, Ameya Joshi, Harish Kumar, Richa Giri, Sanjiv Maheshwari, Valluri Satya Prasad, Jitendra Shukla, Rekha M. Chowdaiah, Nutan Kumar Agrawal, Yogesh Rasal, Banshidhar Sahoo, Shweta Bhandari, Ambanna Gowda, Uday Phadke, Pravin Supe, Niranjan Pathak, Ambrish Chandrappa, Ashutosh Sonawane, Yash Bahulikar, Amit Bhaskar, Arunkumar Radhakrishnan, Priyanka Yadav, Sucheta Pandit, Supriya Sonowal, Dipak Patil, Pravin Ghadge, Suyog Mehta   +26 more
wiley   +1 more source

Improved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique

, 2016
Haiying Li,1 Tingting Pan,1 Ying Cui,1 Xiaxia Li,1 Jiefang Gao,1 Wenzhi Yang,1 Shigang Shen2 1Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmacy, 2Key Laboratory of Analytical Science and Technology of Hebei Province,
Cui Y, Gao JF, Shen SG, Li HY, Li XX, Yang WZ, Pan TT   +6 more
core  

A discriminating dissolution method for glimepiride polymorphs

, 2012
Glimepiride, an oral antidiabetic drug, is practically insoluble in water and exists in two polymorphic forms, I and II, of which form II has higher solubility in water.
Sumaia A. Pires, Hérida R.N. Salgado, Bonfilio, Rudy, Salgado, Hérida Regina Nunes, Adélia E. de Almeida, de Almeida, Adelia E. [UNESP], Pires, Sumaia A., de Almeida, Adelia E., Bonfilio, Rudy [UNESP], Rudy Bonfilio, Doriguetto, Antonio C., Salgado, Hérida Regina Nunes [UNESP], Ferreira, Leonardo M. B., Magali B. de Araújo, Antônio C. Doriguetto, Leonardo M.B. Ferreira, Ferreira, Leonardo M. B. [UNESP], de Araujo, Magali B.   +17 more
core   +1 more source

Fixed-dose combination rosiglitazone/glimepiride in the treatment of type 2 diabetes mellitus [PDF]

, 2006
Rosiglitazone and glimepiride are effective antihyperglycemic agents approved for the treatment of Type 2 diabetes mellitus. Primarily, rosiglitazone increases insulin sensitivity, while glimepiride stimulates insulin release from β-cells in the pancreas.
Salvadeo S., CICERO, ARRIGO FRANCESCO GIUSEPPE, Salvadeo SAT, Giuseppe Derosa, Arrigo FG Cicero, DEROSA, GIUSEPPE, Derosa G., Sibilla AT Salvadeo, Cicero AFG   +8 more
core   +1 more source

A Contribution to the Glimepiride Dissociation Constant Determination

, 2010
Knowledge of druglike properties, such as dissociation constants (pK(a)), is of great importance in drug development and analysis. However, poor aqueous Solubility often Causes serious limitations ill accurate determination of a drug's pK(a).
Parojčić, Jelena, Maksimović, Milica, Sandra Grbic, Andjelija Malenovic, Đurić, Zorica, Zorica Djuric, Malenović, Anđelija, Jelena Parojcic, Milica Maksimovic, Cvijić, Sandra   +9 more
core   +1 more source

Differential interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor I. Binding characteristics [PDF]

, 1994
Glimepiride is a novel sulfonylurea drug for treatment of non-insulin-dependent diabetes mellitus with higher blood sugar lowering efficacy in diabetic patients than glibenclamide raising the question whether this characteristics is in line with ...
Kramer, Werner, Hartz, Detlev, Ökonomopulos, Raymond, Pünter, Jürgen, Müller, Günter, Günter Müller, Werner Kramer, Jürgen Pünter, Raymond Ökonomopulos, Detlev Hartz   +9 more
core   +1 more source

Differential effects of vildagliptin and glimepiride on glucose fluctuations in patients with type 2 diabetes mellitus assessed using continuous glucose monitoring

, 2013
AimTo assess whether there is a difference in the effects of vildagliptin and glimepiride on glucose fluctuation in patients with type 2 diabetes mellitus (T2DM) using continuous glucose monitoring (CGM).MethodsThis was an open-label, randomized cross ...
Neelakantham, S, Kulmatycki, K, He, YL, Mattapalli, D, Foteinos, G, Forst, T, Taylor, A   +6 more
core  

Short-term efficacy and safety of repaglinide versus glimepiride as augmentation of metformin in treating patients with type 2 diabetes mellitus

, 2019
Jing Xie,1 Ning Li,1 Xiaoyan Jiang,1 Liyin Chai,1 Jian-Jun Chen,2 Wuquan Deng11Department of Endocrinology and Nephrology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, People’s Republic of China ...
Chai L, Xie J, Jiang X, Chen JJ, Deng W, Li N   +5 more
core  

Investigation of the Effect of Canagliflozin on the Disposition Index, a Marker of Pancreatic Beta Cell Function, in Patients with Type 2 Diabetes

Diabetes, Metabolic Syndrome and Obesity, 2020
Mitsuyoshi Takahara,1 Toshihiko Shiraiwa,2 Taka-aki Matsuoka,3 Kaoru Yamamoto,2 Yoshifumi Maeno,2 Yuka Shiraiwa,2 Yoko Yoshida,2 Naoto Katakami,4 Hiroaki Iijima,5 Hideyuki Katsumata,6 Kenji Arakawa,5 Toshio Hashimoto,5 Iichiro Shimomura3 1Department of ...
Takahara M, Shiraiwa T, Matsuoka TA, Yamamoto K, Maeno Y, Shiraiwa Y, Yoshida Y, Katakami N, Iijima H, Katsumata H, Arakawa K, Hashimoto T, Shimomura I   +12 more
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