Results 111 to 120 of about 222,357 (321)

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

A radioautographic study of a human brain and glioblastoma multiforme after the in vivo uptake of tritiated thymidine [PDF]

open access: bronze, 1960
H. A. Johnson   +6 more
openalex   +1 more source

Terahertz Metamaterial Sensors: Design Theory, Optimization Approach, and Advancements in Biosensing Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This review provides an in‐depth overview of the design principles and optimization strategies for terahertz (THz) metamaterials (MMs) sensors based on the dielectric perturbation theory. Various structures and methods are explored to enhance sensor performance, focusing on improving sensitivity and Q‐factor.
Lei Cao   +9 more
wiley   +1 more source

MicroRNA-613 is downregulated in HCMV-positive glioblastoma and inhibits tumour progression by targeting arginase-2

open access: yesTumor Biology, 2017
Glioblastoma is the most common and malignant tumour that occurs primarily in nervous system and has a high morbidity. Research on glioblastoma has recently focused on human cytomegalovirus, belonging to the beta subfamily of Herpesviridae that plays ...
Yan Wang   +6 more
doaj   +1 more source

A Topological Data Analysis Framework for Quantifying Necrosis in Glioblastomas [PDF]

open access: yesarXiv
In this paper, we introduce a shape descriptor that we call "interior function". This is a Topological Data Analysis (TDA) based descriptor that refines previous descriptors for image analysis. Using this concept, we define subcomplex lacunarity, a new index that quantifies geometric characteristics of necrosis in tumors such as conglomeration ...
arxiv  

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

open access: yesAdvanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu   +21 more
wiley   +1 more source

Rapid Progression of Gliomatosis Cerebri to Secondary Glioblastoma, Factors That Affect the Progression Rate: A Case Report

open access: yes대한영상의학회지, 2017
Glioblastomas may develop de novo or through progression from low-grade or anaplastic astrocytomas. The term ‘primary glioblastoma’ refers to a glioblastoma that lacks a precursor lesion and has a clinical history of less than three months.
Hee Kyung Kim   +5 more
doaj   +1 more source

Radiogenomic biomarkers for immunotherapy in glioblastoma: A systematic review of magnetic resonance imaging studies [PDF]

open access: yes
Immunotherapy is an effective precision medicine treatment for several cancers. Imaging signatures of the underlying genome (radiogenomics) in glioblastoma patients may serve as preoperative biomarkers of the tumor-host immune apparatus. Validated biomarkers would have the potential to stratify patients during immunotherapy clinical trials, and if ...
arxiv   +1 more source

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