Results 131 to 140 of about 263,515 (247)

High intra-tumoral and serum matrix metalloproteinase 9 levels are associated with reduced survival of patients with glioblastoma and brain metastases. [PDF]

Front Oncol
Kaisman-Elbaz T, Haddad-Shlaifshtein S, Eskira Y, Merkin V, Dumanis G, Turiel S, Atar-Vardi M, Bari R, Alt A, Zamed T, Rotem-Dai N, Lavrenkov K, Kezerle Y, Dyomin V, Razon R, Chakraborty M, Asraf H, Hershfinkel M, Melamed I.   +18 more
europepmc   +1 more source

JS03.5.A DO PATIENTS WITH MOLECULARLY-DEFINED GLIOBLASTOMA SHARE THE SAME CLINICAL CHARACTERISTICS AND OUTCOME OF HISTOLOGICALLY-DEFINED GLIOBLASTOMA? A MULTICENTRIC STUDY FROM THE ITALIAN ASSOCIATION OF NEURO-ONCOLOGY (AINO) [PDF]

Francesco Bruno, A Pellerino, Luca Bertero, Antonio Silvani, Bianca Pollo, Tamara Ius, Stefano Pizzolitto, M Conti Nibali, Giulia Berzero, Pierina Navarria, Lorena Gurrieri, Anna Luisa Di Stefano, M Maccari, Giuseppe Lombardi, V Internò, Edoardo Pronello, Maria Caffo, Quintino Giorgio D’Alessandris, R Soffietti, Diego Garbossa, Lorenzo Bello, Roberta Rudà   +21 more
openalex   +1 more source

MicroRNA‐221 targeting PI3‐K/Akt signaling axis induces cell proliferation and BCNU resistance in human glioblastoma [PDF]

, 2014
Qiang Xie, Yongrong Yan, Zuoping Huang, Xueyun Zhong, Lei Huang   +4 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Correlation of Galectin Family Expression with Glioblastoma Progression and Survival. [PDF]

Int J Mol Sci
Curpen P, Ahmady F, Carnie BMH, Anderson GEC, Kannourakis G, Sharma A, Achuthan AA, Luwor RB.   +7 more
europepmc   +1 more source

P16.01.B DOXORUBICIN GLYCOSYLATION AS A NOVEL APPROACH TO SPECIFICALLY TARGET GLIOBLASTOMA [PDF]

Anna Lisa Iorio, Chiara Marzano, Bianca Tirinnanzi, Edoardo Lenci, Elisabetta Bucaletti, B Castelli, Carla Fonte, M Tellini, Milena Guidi, Marco Di Nicola, Laura Giunti, Claire Torre, Andrea Trabocchi, Iacopo Sardi   +13 more
openalex   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Role of elevation of glycolysis in tumor-associated macrophages in glioblastoma immune evasion and therapeutic implications. [PDF]

PNAS Nexus
Chen J, Zhu L, Lawson T, Proud CG, Dai L.   +4 more
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Treatment differences in IDH-wildtype glioma - the impact of surgery and adjuvant therapy. [PDF]

J Neurooncol
Keric N, Krenzlin H, Lange F, Dauth A, Freyschlag CF, Schnellg O, Misch M, von der Brelie C, Gempt J, Krigers A, Wagner A, Mielke D, Sommer C, Brockmann MA, Meyer B, Rohde V, Vajkoczy P, Beck J, Thomé C, Ringel F.   +19 more
europepmc   +1 more source