Harnessing ferroptosis to transform glioblastoma therapy and surmount treatment resistance. [PDF]
Singh S+7 more
europepmc +1 more source
Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. [PDF]
Candece L. Gladson, D A Cheresh
openalex +1 more source
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan+5 more
wiley +1 more source
Expression of Glial Cell Line-derived Neurotrophic Factor and Its Receptors in Glioblastoma. [PDF]
Ewald JD+6 more
europepmc +1 more source
GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation
Schematic diagram of the mechanism by which GSK461364 inhibits NLRP3 inflammasome activation. GSK461364 inhibits the phosphorylation of NEK7 likely at serine 221 and serine 260 by suppressing the activity of PLK1, thereby restraining the formation of the NLRP3 inflammasome.
Ruiheng Luo+13 more
wiley +1 more source
Aberrant neuronal firing: a paracrine route to glioblastoma expansion. [PDF]
Lee JY, Koo BI, Le-Kim TH, Nam Y.
europepmc +1 more source
Activation of human platelet-derived latent transforming growth factor-β1 by human glioblastoma cells. Comparison with proteolytic and glycosidic enzymes [PDF]
Damon Huber, A. Fontana, Stefan Bodmer
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From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen+7 more
wiley +1 more source
Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics. [PDF]
Zhao J+26 more
europepmc +1 more source
Pharmacokinetics and Tolerance of Nicotinamide Combined with Radiation Therapy in Patients with Glioblastoma Multiforme [PDF]
F. Cartei+6 more
openalex +1 more source