Results 161 to 170 of about 252,843 (247)

Computer-assisted analysis of the microvasculature in untreated glioblastomas [PDF]

open access: green, 1995
Pieter Wesseling   +4 more
openalex   +1 more source

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou   +7 more
wiley   +1 more source

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang   +21 more
wiley   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells. [PDF]

open access: hybrid, 1995
Erwin G. Van Meir   +9 more
openalex   +1 more source

NQO1/p65/CXCL12 Axis‐Recruited Tregs Mediate Resistance to Anti‐PD‐1 Plus Lenvatinib Therapy in PIVKA‐II‐Positive Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
High PIVKA‐II expression in HCC correlates with resistance to anti‐PD‐1 plus lenvatinib, driven by an immunosuppressive TME. NQO1/p65/CXCL12 axis recruits Tregs to promote resistance to anti‐PD‐1 plus lenvatinib in HCC with high PIVKA‐II expression.
Biao Gao   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy