Results 181 to 190 of about 252,843 (247)

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

Advanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen, Yuexuan Xu, Ying Xu, Xiao Liu, Yuting Zhang, Dan Ye, Sai Han, Shili Liu, Youzhong Zhang   +8 more
wiley   +1 more source

Advances in neuroscientific mechanisms and therapies for glioblastoma. [PDF]

iScience
Li K, Duan M, Lu Q, Liu J, He M, Zhang Y.   +5 more
europepmc   +1 more source

Human Glioblastoma Cells Produce Granulocyte-macrophage Colony-stimulating Factor In Vitro, but Not In Vivo, Without Expressing Its Receptor

, 1993
Junichi Murata, Yutaka Sawamura, Mitsuhiro Tada, Shiro Sakuma, Masako Sudo, Toshimitsu Aida, Hiroshi Abe   +6 more
openalex   +2 more sources

Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy

Advanced Science, EarlyView.
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang, Fan Tong, Jiantao Chen, Muzaffar Kayumov, Yue Lv, Yajun Shi, Bengui Ye, Huile Gao   +7 more
wiley   +1 more source

Single-cell in situ mapping of glioblastoma and astrocyte cell lines treated with a carbon dot-mediated riluzole nanotherapeutic agent: a live-cell µFTIR and soft X-ray tomography approach. [PDF]

J Nanobiotechnology
Dučić T, Pereiro E, Ninkovic M, Sperling S, Rohde V, Fernández-González C, Algarra M, González-Muñoz E.   +7 more
europepmc   +1 more source

Modulation of Proliferation and Antigen Expression of a Cloned Human Glioblastoma by Interleukin-4 Alone and in Combination with Tumor Necrosis Factor-α and/or Interferon-γ

, 1993
Koichi Iwasaki, Lisa R. Rogers, Melinda L. Estes, Barbara P. Barna   +3 more
openalex   +1 more source

Single‐Cell Nucleus Extraction with Cellular Indexing

Advanced Science, EarlyView.
VacTrap is a multilayer, high‐throughput microfluidic system that isolates and spatially indexes single nuclei from hundreds of cells within minutes. Using dissolvable hydrogel trapdoors triggered by chemical and vacuum actuation, VacTrap synchronously transfers nuclei while preserving spatial links to parent cells.
Trinh Lam, Ana Esmeralda Gomez Martinez, Alison Su, Anna Fomitcheva‐Khartchenko, Xin Wang, Md Nazibul Islam, Paul Lum, Amy Elizabeth Herr   +7 more
wiley   +1 more source

Targeting the Mitochondria in High-Grade Gliomas. [PDF]

Cancers (Basel)
Sathe S, Li Q, Jung J, Wu J.
europepmc   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

Aggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang, Yanyu Chen, Shile Wang, Kan Liu, Xing‐Zhong Zhao, Xiaobo Mao, Ben Zhong Tang, Lang Rao   +7 more
wiley   +1 more source

Assessing Large Multimodal Models for One‐Shot Learning and Interpretability in Biomedical Image Classification

Advanced Intelligent Systems, EarlyView.
Image classification plays a pivotal role in biomedical image analysis. Herein, it is shown that large multimodal models, such as GPT‐4, achieve superior performance in one‐shot learning, generalization, interpretability, and text‐driven image classification. Applications span tissue, cell type, cellular state, and disease classification, outperforming
Wenpin Hou, Qi Liu, Huifang Ma, Yilong Qu, Zhicheng Ji   +4 more
wiley   +1 more source