Results 191 to 200 of about 319,103 (346)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

GLIOBLASTOMA

open access: yes, 2018
Aditya Juloori   +2 more
openaire   +2 more sources

Deciphering glioblastoma pathogenesis: Insights from mitophagy dysregulation and SNX7 as a therapeutic target

open access: yesBrain Research Bulletin
Background: Glioblastoma is a highly aggressive and invasive brain tumor with an extremely poor prognosis. The aims of the present study are to investigate the pathogenesis of glioblastoma and identify potential therapeutic targets. Methods: We performed
Yuanlong Zhang   +4 more
doaj  

Cytokine regulation of intercellular adhesion molecule-1 (ICAM-1) expression on human glioblastoma cells [PDF]

open access: bronze, 1990
Maria C. Kuppner   +3 more
openalex   +1 more source

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin   +14 more
wiley   +1 more source

Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas. [PDF]

open access: yesNat Commun
Webb MG   +10 more
europepmc   +1 more source

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

open access: yesAdvanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin   +12 more
wiley   +1 more source

Molecular Biomarkers of Glioma. [PDF]

open access: yesBiomedicines
Rajakaruna P   +11 more
europepmc   +1 more source

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