CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou+15 more
wiley +1 more source
Evaluating the Antitumor Potential of Cannabichromene, Cannabigerol, and Related Compounds from <i>Cannabis sativa</i> and <i>Piper nigrum</i> Against Malignant Glioma: An In Silico to In Vitro Approach. [PDF]
Turizo Smith AD+4 more
europepmc +1 more source
A Syngeneic Mouse Glioma Model for Study of Glioblastoma Therapy [PDF]
Ned E. Weiner+7 more
openalex +1 more source
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
D. Keskin+50 more
semanticscholar +1 more source
Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface
Drop‐on‐demand printing is used to replicate the spatial compartmentalization of the breast cancer‐host interface. Hydrogel confinement affects phenotypic changes in cells at the spheroid interface that drives a two‐fold increase in chemotherapeutic resistance compared to control unconfined spheroids.
Bram G. Soliman+4 more
wiley +1 more source
Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas
Kazunari Yachi+7 more
openalex +2 more sources
Chromosome 7 Rearrangements in Glioblastomas; Loci Adjacent to EGFR Are Independently Amplified [PDF]
Lu Liu+3 more
openalex +1 more source
Magnetoelectric (ME) core–shell nanoparticles, particularly made of CoFe2O4‐BaTiO3, are emerging as promising materials for bioengineering applications. This perspective explores the evolution of measurement methodologies for their ME coefficient (α), highlighting variations in reported values.
Martina Lenzuni+4 more
wiley +1 more source
Dual-Plasma Discharge Tube for Synergistic Glioblastoma Treatment. [PDF]
Murphy W+4 more
europepmc +1 more source