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Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023
Glioblastoma is one of the most common and invasive types of primary brain malignancies in adults, accounting for 45.5% of malignancies. Its annual prevalence is low compared to other cancers. The survival rate of this disease is about 14 months after diagnosis.
Zahra Jodari, Mohammadpour   +6 more
openaire   +3 more sources

Investigation of the Role of Induced Overexpression of the Isolated Secreted Klotho on the A-172 Human Glioblastoma Cells

Journal of Molecular Neuroscience, 2022
Klotho gene, identified in 1997 as an anti-aging gene, can manufacture two protein products: transmembrane and secreted forms. The later research revealed the involvement of klotho in carcinogenesis. However, little is known about the action of different Klotho forms on antitumor effects is still.
Vsevolod V. Melekhin   +3 more
openaire   +3 more sources

Immunocytochemical studies on the effect of 405-nm low-power laser irradiation on human-derived A-172 glioblastoma cells

Lasers in Medical Science, 2011
The application of low-power laser irradiation (LLI) affects the cell cycle and cell proliferation in various kinds of cells. LLI at a wavelength of 808 nm and a power of 30 mW has been found to significantly decrease the proliferation rate of cells of the human-derived glioblastoma cell line A-172. To determine if this effect of LLI is specific to 808-
Foong Yee, Ang   +3 more
openaire   +3 more sources

Effects of low-power laser irradiation on proliferation of human-derived glioblastoma A-172

Neuroscience Research, 2009
Hideyuki Murayama   +3 more
openaire   +2 more sources

Abstract 2535: Inhibition of oncogenic ASPP2kappa(k), a dominant-negative isoform of the tumorsuppressor ASPP2, results in reactivation of p53 in glioblastoma

Cancer Research, 2023
GB is the most common, most aggressive primary brain tumor with a deleterious prognosis. Novel approaches to improve therapy are urgently needed. ASPP2 is a tumor suppressor, directly interacting with p53 to induce apoptosis.
M. Hafner   +9 more
semanticscholar   +1 more source

P15.05.B THE IMPACT OF IOMRI ON GLIOBLASTOMA RESECTION AND CLINICAL OUTCOMES IN A STATE-OF-THE-ART NEURO-ONCOLOGICAL SETUP

Neuro-Oncology, 2023
Intraoperative magnetic resonance imaging (ioMRI) is applied to improve the extent of resection in patients suffering from primary brain tumors, especially glioblastoma (GBM).
M. Schwendner   +5 more
semanticscholar   +1 more source

Abstract 1822: Selective inhibition of ZCCHC11/ZCCHC6 TUTases with genetic and pharmacological tools supports a role in glioblastoma cell growth

Cancer Research, 2022
The purpose of the study was to determine if genetic and pharmacological inhibition of terminal uridyltransferases (TUTases) ZCCHC11 and ZCCHC6 could modulate Glioblastoma (GBM) cell growth in vitro.
Robinson Triboulet   +13 more
semanticscholar   +1 more source

DISP-16. EXPLORING SEX-BASED DIFFERENCES IN RESPONSE TO IMMUNOTHERAPY IN GLIOBLASTOMA: A RETROSPECTIVE REVIEW

Neuro-Oncology
The prognostic implication of sex is unclear in glioblastoma. A recent preclinical study suggested that T-cell exhaustion in males confers improved response to anti-PD1 therapy (PMID: 37378557).
Catharina Westergaard   +17 more
semanticscholar   +1 more source

DDDR-01. Efficacy of triple combination therapy with temozolomide, interferon-beta and ribavirin against glioblastoma cells

Neuro-Oncology
The antitumor effects of interferon-beta or ribavirin against glioblastoma cells have been reported in several studies. We investigated the antitumor effects of combination therapy consisting of temozolomide, interferon-beta, and ribavirin on ...
S. Yamamuro   +7 more
semanticscholar   +1 more source

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