Results 141 to 150 of about 49,717 (158)
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Identification of indirect pathways enhancing the biocompatibility of DOX/GO/Fe3O4 nanomaterials in Glioblastoma: Gene network modeling and pathway analysis.

Biochemical and Biophysical Research Communications - BBRC
BACKGROUND Glioblastoma multiforme (GBM) is the most common primary malignant tumor of the central nervous system. Conventional treatment includes maximal safe surgical resection combined with radiotherapy and chemotherapy.
Amin Alvani   +7 more
semanticscholar   +1 more source

Evaluation of L-methioninase as a targeted anticancer therapy in ovarian cancer and glioblastoma

AIMS Biophysics
: Background and objective: A characteristic feature of many cancer cells, including glioblastoma and ovarian carcinoma, is their reliance on exogenous methionine for tumor proliferation.
Abbas Abed Noor Al-Owaidi   +1 more
semanticscholar   +1 more source

Distinct modes of death in human neural stem and glioblastoma cells irradiated with carbon-ion radiation and gamma-rays

International Journal of Radiation Biology, 2020
Purpose: Accumulated damage in neural stem cells (NSCs) during brain tumor radiotherapy causes cognitive dysfunction to the patients. Carbon-ion radiotherapy can reduce undesired irradiation of normal tissues more efficiently than conventional photon ...
Y. Yokota, Yutaka Wada, T. Funayama
semanticscholar   +1 more source

EXTH-01. EFFICACY OF PERAMPANEL AGAINST GLIOBLASTOMA CELLS

Neuro-Oncology
We investigated the antitumor effect of perampanel, which is the AMPA-type glutamate receptor antagonist widely used as an antiepileptic drug in Japan, on glioblastoma cells both in vitro and vivo. Commercially available glioblastoma cell lines (A-172,
S. Yamamuro   +9 more
semanticscholar   +1 more source

Preclinical Study of Cannflavins A and B Action Against Glioblastoma Cells

bioRxiv
Background Flavonoids represent a large group of naturally occurring polyphenolic compounds, many of which have been found to produce valuable biological outcomes, including action against cancer cells. Glioblastoma multiforme (GBM) is an aggressive type
Jennifer Holborn   +10 more
semanticscholar   +1 more source

The effect of miR‐579 on the PI3K/AKT pathway in human glioblastoma PTEN mutant cell lines

Journal of Cellular Biochemistry, 2019
Glioblastoma multiform (GBM) is a type of aggressive brain cancer with limited success in standard treatment. MicroRNAs are one of the most beneficial tools for diagnosis, prognosis, and treatment of cancer.
Mohammad Reza Kalhori   +4 more
semanticscholar   +1 more source

Culture Dimensionality Modulates Gallium Maltolate Response in Glioblastoma: Comparative Analyses in 2D and 3D Models.

Molecular Pharmaceutics
Gallium maltolate (GaM) targets iron-dependent processes in glioblastoma (GBM), but responses vary with the model context. We evaluated GaM across established (A-172, U-87 MG) and patient-derived (3005, 3019, 3034, 3048, 3073) GBM lines in 2D and 3D ...
Paulina Szeliska   +5 more
semanticscholar   +1 more source

Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172.

Journal of biochemistry, 1995
Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. The inducible type of nitric oxide synthase (NOS) is considered to be a key molecule in the immune responses to bacteria, parasites, and tumors, and its gene expression is regulated by cytokines. We isolated 3 overlapping partial inducible NOS cDNA clones from a human
A, Hokari, M, Zeniya, H, Esumi
openaire   +1 more source

CFTR activation suppresses glioblastoma cell proliferation, migration and invasion.

Biochemical and Biophysical Research Communications - BBRC, 2019
The aim of this study was to investigate the function of Cystic fibrosis transmembrane conductance regulator (CFTR) in human glioblastoma (GBM) cells. Data dining results of the Human Protein Atlas showed that low CFTR expression was associated with poor
Xiao Zhong   +5 more
semanticscholar   +1 more source

Differentiation between glioblastoma and primary CNS lymphoma: application of DCE-MRI parameters based on arterial input function obtained from DSC-MRI

European Radiology, 2021
Koung Mi Kang   +11 more
semanticscholar   +1 more source

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