Results 81 to 90 of about 115,602,437 (109)
Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma
, 2015 Primary and secondary glioblastomas (GBMs) are two distinct diseases. The genetic and epigenetic background of these tumors is highly variable. The treatment procedure for these tumors is often unsuccessful because of the cellular heterogeneity and ...
Rasime Kalkan
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Small, Volume 22, Issue 49, 1 September 2026.Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley +1 more source
The role of mitochondrial DNA in the tumor biology of glioblastoma multiforme and multiple myeloma [PDF]
Cancer cells preferentially metabolise glucose via aerobic glycolysis (the Warburg effect), which is less energy efficient in teens of ATP production compared to oxidative phosphorylation (OXPHOS).
Yeung, Ka Yu
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Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
Cell Proliferation, Volume 59, Issue 9, September 2026.m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Cell Proliferation, Volume 59, Issue 9, September 2026.Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
A new mathematical model for radiation cell killing mechanism: Target cumulating model [PDF]
, 2009 There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin +3 more
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Clinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field.
Brem, Steven,editor. +1 more
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Isolation and characterization of a human glioblastoma cell line
, 2007 The characterization of a glioblastoma cells line represents an important achievement in the field of brain tumor research activity, which enables the researchers to obtain strong results with a wide recognition by the scientific community. The objective
Tascu, A. +6 more
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Journal of biochemistry, 1995
Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. The inducible type of nitric oxide synthase (NOS) is considered to be a key molecule in the immune responses to bacteria, parasites, and tumors, and its gene expression is regulated by cytokines. We isolated 3 overlapping partial inducible NOS cDNA clones from a human
A, Hokari, M, Zeniya, H, Esumi
openaire +1 more source
Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. The inducible type of nitric oxide synthase (NOS) is considered to be a key molecule in the immune responses to bacteria, parasites, and tumors, and its gene expression is regulated by cytokines. We isolated 3 overlapping partial inducible NOS cDNA clones from a human
A, Hokari, M, Zeniya, H, Esumi
openaire +1 more source