Results 201 to 210 of about 540,674 (406)
Optic glioma of childhood. Natural history and rationale for conservative management. [PDF]
, 1969 William F. Hoyt, Sahag A. Baghdassarian
openalex +1 more source
Advanced Science, EarlyView.PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue +10 more
wiley +1 more source
PSEUDO-GLIOMA DUE TO LARVAL CHOROIDO-RETINAL GRANULOMATOSIS [PDF]
, 1961 William R. Harris
openalex +1 more source
A Complementarity‐Based Approach to De Novo Binder Design
Advanced Science, EarlyView.A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko +17 more
wiley +1 more source
Genetic and molecular epidemiology of adult diffuse glioma
Nature Reviews Neurology, 2019 A. Molinaro +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang +15 more
wiley +1 more source
Advanced Science, EarlyView.FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan +5 more
wiley +1 more source
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
New England Journal of Medicine, 2015 J. Eckel-Passow +35 more
semanticscholar +1 more source