Results 191 to 200 of about 194,510 (268)

Modeling gliomas with organoids: reconstructing the human neural microenvironment for translational neuro-oncology. [PDF]

Front Oncol
Ishan M, Jimenez-Macias JL, Read RD.
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

IDH1-Associated m6A Methylation Is Linked to Transcriptomic Heterogeneity in Glioma. [PDF]

Cancers (Basel)
Batool SM, Lee H, Muralidharan K, Khan SM, Escobedo AK, Gashi D, Faber K, Barretts NR, Ekanayake E, Hsia T, Al-Inaya Y, Kosgi A, Miller JJ, Cahill DP, Dunn GP, Choi BD, Petti AA, Carter BS, Balaj L.   +18 more
europepmc   +1 more source

Functional Imaging for Identification of Functionally Critical Brain Regions to Spare in Glioma Radiation Therapy Planning: A Systematic Review

Journal of Medical Radiation Sciences, EarlyView.
This review highlights the role of functional imaging in sparing cognitive brain regions during glioma radiotherapy. It shows promising dose reduction without compromising target coverage, but evidence remains limited, requiring standardisation and prospective validation.
Li Wen Yeo, John T. Ryan
wiley   +1 more source

Emerging frontiers in glioma therapy: the evolving role of glioma vaccines. [PDF]

Front Immunol
Gao R, Gong Z, He Y, Jiang Y, Duan H, Wang H.   +5 more
europepmc   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

GLOBE: an explainable machine learning platform for preoperative prediction of thromboembolism and neurological deterioration in patients with glioma. [PDF]

Front Neurosci
Xiang F, Yang X, Xiang S, Fu M, Yang G.
europepmc   +1 more source

Rhaponticin Blocks Glycolysis‐Mediated Histone Lactylation to Suppress Tongue Squamous Cell Carcinoma via HIF‐1α Activity Inhibition

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu, Liang‐Liang Yao, Lin Jiang, Zhi‐Yi Fang, Jia‐Jun Zhu, Yi‐Sen Shao, Wen‐Juan Wang, Xiao‐Wen Wan   +7 more
wiley   +1 more source

A novel risk model of cholesterol metabolism-related mRNAs for predicting overall survival and immune signature in glioma based on machine learning and multi-omics data. [PDF]

Transl Cancer Res
Yu D, Shen K, Wang J, Jiang F, Xia P, Yu Z.   +5 more
europepmc   +1 more source