Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells
Yingge Wang +3 more
openalex +2 more sources
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye +14 more
wiley +1 more source
Venous Thromboembolism and Bleeding with Temozolomide-, Bevacizumab-, and Nitrosourea-Based Therapy in Glioma: A Dual-Database Pharmacovigilance Study. [PDF]
Hou X, Zhang Y, Liang C, Yao S.
europepmc +1 more source
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
Constructing anoikis-related signatures in glioma and identifying PLAU as a new prognostic biomarker. [PDF]
Tong H +9 more
europepmc +1 more source
Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan +8 more
wiley +1 more source
Chromatin accessibility derived from cfDNA serves as a novel classification biomarker of glioma. [PDF]
Wu Q +11 more
europepmc +1 more source
Preoperative Detection of Dual TERT Promoter Mutations in Thyroid Cancer: A Case Series
ABSTRACT Telomerase reverse transcriptase promoter (TERTp) mutations are associated with aggressive thyroid cancer and are most frequently found in anaplastic and poorly differentiated thyroid cancer. Pre‐operative thyroid nodule molecular testing can detect TERTp, denoting a high risk of malignancy and possible aggressive clinical features such as ...
Amir Harari +7 more
wiley +1 more source
Terahertz attenuated total reflection imaging of fresh brain glioma based on a solid immersion lens. [PDF]
Li H +7 more
europepmc +1 more source
Necroptotic signaling orchestrates glioblastoma malignancy and potentiates temozolomide response. [PDF]
Li Y +12 more
europepmc +1 more source

