Results 261 to 270 of about 412,622 (340)

Characterization of lysine crotonylation-related lncRNAs for prognostic assessment and immune response in glioma. [PDF]

Front Pharmacol
Song M, Xu J, Gui Z, Wu Y, Wang F, Sheng H, Huang X, Qian J, Qin H, Wang Y.   +9 more
europepmc   +1 more source

Chromenone Derivatives as CRM1 Inhibitors for Targeting Glioblastoma

ChemBioChem, EarlyView.
Chromenone derivatives are synthesized and evaluated as inhibitors of chromosome region maintenance 1‐mediated nuclear export, targeting glioblastoma cells. Active compounds demonstrate structure‐ and dose‐dependent inhibition, supported by structure–activity relationships and molecular docking studies.
Salvatore Princiotto, Lucía Jiménez, Lucía Domínguez, João G. N. Sequeira, Cristiana Mourato, Alba Orea‐Soufi, Bruno Santos, Sabrina Dallavalle, Miguel Machuqueiro, Bibiana I. Ferreira, Wolfgang Link   +10 more
wiley   +1 more source

Comparative efficacy of glioma treatment strategies: an umbrella review of meta-analyses. [PDF]

Ann Med
Yang E, Yang Y, Gao Y, Liu X, Liu X, Zong X, Li J.   +6 more
europepmc   +1 more source

Specific visualization of glioma cells in living low-grade tumor tissue. [PDF]

, 2010
Arndt-Jovin, D., Caarls, W., de Vries, A., Giese, A., Hagen, G., Jovin, T., Kantelhardt, S., Rohde, V., Schulz-Schaeffer, W.   +8 more
core   +1 more source

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes

Cell Biology International, EarlyView.
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio, Ariely Barbosa Leite, Ana Caroline de Castro Nascimento Sousa, Suellen Rodrigues Maran, Antoniel Augusto Severo Gomes, Elton J. R. Vasconcelos, Nilmar Silvio Moretti   +6 more
wiley   +1 more source

The Effects of Castration on the Induction of Experimental Gliomas in Male Rats

, 1970
J. W. Hopewell
openalex   +1 more source

Integrative analysis of crotonylation-associated genes reveals prognostic and therapeutic targets in gliomas. [PDF]

Front Oncol
Yin B, Fan Z, Yu P, Li J, Wang Y, Shu M.
europepmc   +1 more source

Bioresponsive Hyaluronic Acid‐Based Hydrogel Inhibits Matrix Metalloproteinase‐2 in Glioblastoma Microenvironment

ChemMedChem, EarlyView.
A bioresponsive hydrogel based on hyaluronic acid crosslinked with a MMP inhibitor (HA‐MMPI) is generated to modulate the glioblastoma multiforme (GBM) microenvironment. In preliminary tests with 3D U87 models, HA‐MMPI selectively inhibits MMP‐2, reducing cell migration.
Federica Barbugian, Domenico Salerno, Elisa Ballarini, Luca Crippa, Oscar Francesconi, Francesco Mantegazza, Guido Cavaletti, Stefano Roelens, Gemma Leone, Simone Pepi, Luigi Talarico, Agnese Magnani, Cristina Nativi, Laura Russo   +13 more
wiley   +1 more source

Bibliometric and visualization analysis of glioma pharmacotherapy from 2020 to 2024. [PDF]

Front Neurol
Hong X, Wei Z, Zuo T, Xu L, Zhang H, Xu T, Wang D, Lu C, Hou L.   +8 more
europepmc   +1 more source

Taste Profile and Relative Bioavailability of Tovorafenib Powder for Oral Suspension and Food Effect of the Tovorafenib Tablet in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang, Mike Preigh, Jing Wang, Eleni Venetsanakos, Yujin Wang, Elly Barry, Don Corson   +6 more
wiley   +1 more source