Results 291 to 300 of about 412,622 (340)

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Potential Therapeutic Appliances of Dietary Polyphenols: Resveratrol and Curcumin in Treatment of Gliomas. [PDF]

open access: yesInt J Mol Sci
Smolińska E   +5 more
europepmc   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

open access: yesExploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao   +15 more
wiley   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

open access: yesFood Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee   +4 more
wiley   +1 more source

The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Hawthorn: A Review

open access: yesFood Frontiers, EarlyView.
This review systematically and comprehensively analyzes hawthorn (Crataegus spp.), covering its bioactive constituents, properties, and processed products. ABSTRACT Hawthorn is widely cultivated in China, with excellent varieties and steadily increasing production.
Wenteng Yang   +7 more
wiley   +1 more source

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