Results 231 to 240 of about 79,800 (306)
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park +19 more
wiley +1 more source
Hypothalamic gliosis as a potential mediator of improved glucose tolerance induced by time-restricted feeding in obese mice. [PDF]
Astudillo-Guerrero C +6 more
europepmc +1 more source
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen +13 more
wiley +1 more source
Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer's disease retina. [PDF]
Gaire BP +22 more
europepmc +1 more source
Abstract INTRODUCTION We examined how neurovascular and astrocytic response alter cognition in Alzheimer's disease (AD). METHODS Cognitive scores, biomarkers of AD and astrocytic activation, vascular factors, and brain structure data from 693 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants were analyzed using analysis of covariance ...
Zehu Sheng +12 more
wiley +1 more source
A Canine Case of Gliosis with Cyst Formation in the Posterior Fossa.
Masato Kitagawa +6 more
openalex +2 more sources
ABSTRACT Encephalomalacia, the irreversible loss of brain tissue following injury, is a well‐documented cause of post‐traumatic epilepsy, typically manifesting within the first year. However, delayed‐onset intractable epilepsy in young adults remains underrecognized.
Katrina J. Villegas +4 more
wiley +1 more source
ACOX1 gain-of-function post-mortem neuropathology is distinct from ACOX1 loss-of-function: case report and literature review. [PDF]
Hubler Z +9 more
europepmc +1 more source
Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice
Jia‐zhan Huang et al. describe a function of prefrontal TRPM8 in the regulation of epileptic seizures. TRPM8 receptors was upregulated in the prefrontal cortex (PFC) of epileptic mice. Inhibition or knockdown of TRPM8 in PFC can effectively prolong the latency and reduce the level of seizures in mouse models induced by pentatetrazole. At the same time,
Jia‐Zhan Huang +6 more
wiley +1 more source

