Results 251 to 260 of about 79,800 (306)
Palmitate-Induced Primary Rat Senescent Astrocytes Exhibit Higher Inflammatory Activity and a Distinct Transcriptomic Profile Compared to Reactive Astrocytes. [PDF]
López-Teros M +9 more
europepmc +1 more source
ABSTRACT Cell trafficking disorders(CTDs) are rare, heterogeneous inherited conditions marked by impaired intracellular transport mechanisms such as vesicular trafficking, cytoskeletal dynamics, and organelle interactions. Although clinical awareness is increasing, CTDs are often underdiagnosed due to phenotypic overlap with mitochondrial, lysosomal ...
Merve Yoldaş Çelik +6 more
wiley +1 more source
Liver Transplantation in PNPO Deficiency: Management Challenges and Biological Lessons
ABSTRACT Pyridox(am)ine 5′ Phosphate Oxidase deficiency (PNPO) presents with refractory epilepsy responsive to treatment with pyridoxal 5′ phosphate (PLP) or pyridoxine. A 15‐year‐old boy with PNPO deficiency and cirrhosis underwent orthotopic liver transplantation for hepatocellular carcinoma without extra‐hepatic disease.
Richard Webster +12 more
wiley +1 more source
A retrospective study of 171 cases of equine meningoencephalomyelitis in the United States, 1996-2023. [PDF]
Countrymann K, Ruby R, Miller AD.
europepmc +1 more source
DNA‐Loaded Nanoparticles Reprogram the Tumor Immune Microenvironment to Treat Brain Tumors
Biodegradable poly(beta‐amino ester) nanoparticles can be employed to deliver immunostimulatory genes (4‐1BBL and IL‐12) to reprogram brain tumor cells into antigen‐presenting cells to stimulate an anti‐tumor response, resulting in tumor regression and long‐term survival in GBM and meningioma models.
Joanna Yang +14 more
wiley +1 more source
Systemic (retro‐orbital vein) recurrent injections of human iPSC‐microglia and neural stem cell‐derived extracellular vesicles in a 5xFAD mouse model of Alzheimer's disease significantly improve cortex‐dependent cognitive function, reduce amyloid beta plaques, mitigate microglial and astrocytic activation, deliver neuroprotective miRNA cargo, and ...
Robert P. Krattli Jr. +7 more
wiley +1 more source
Bridging the Cartesian Divide Between Organic and Functional Catatonia: A Case Report. [PDF]
Syed H +3 more
europepmc +1 more source
FAM20C regulates the composition of the YTHDC1‐NCL‐KAP1‐LINE1 RNAs complex, thereby affecting neuronal differentiation in hypoxic–ischemic brain damage (HIBD). ABSTRACT Neurodevelopmental impairment due to hypoxic–ischemic brain damage (HIBD) lacks effective biomarkers and therapeutic targets.
Chen‐xi Feng +8 more
wiley +1 more source

