Results 41 to 50 of about 14,862,239 (364)
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Development prospects for the polish economy
Nowoczesne Systemy Zarządzania, 2018 The market economy develops cyclically, which is reflected in the wave of economic activity. The reasons for the breakdown in economic activity in each cycle are different, but the course of the cycle is similar.
Henryk PAŁASZEWSKI
doaj +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Global Companies and Global Regulation [PDF]
Symphonya. Emerging Issues in Management, 2005 In a global economy, corporate responsibility has to interact with the specific social and environmental aspects of each Nation-State, which consequently are not viewed as local differences but rather as elements of market competition. This interaction has to concentrate on complex matters such as profitability and the protection of financial ...
openaire +5 more sources
Alphaville: Journal of Film and Screen Media, 2016 The Three Amigos charts the careers of three of the most prominent contemporary Mexican filmmakers: Guillermo del Toro, Alejandro González Iñárritu, and Alfonso Cuarón, and their emergence as international filmmakers.
Elliot Hardman
doaj +1 more source
CAN VIRTUE ETHICS BRIDGE EAST AND WEST?
Central Asian Journal of Medical Hypotheses and Ethics, 2021 CAN VIRTUE ETHICS BRIDGE EAST AND WEST?
Nalakath A. Uvais
doaj +1 more source
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2019 Papillomaviruses (PV) are associated with epithelial malignancies in animals, including cancer in humans. Limited knowledge exists regarding the evolutionary history of non-human PV.
Alba Frias-De-Diego +2 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source