Results 101 to 110 of about 9,762 (294)

Global attractor in competitive Lotka–Volterra systems [PDF]

open access: yesMathematische Nachrichten, 2009
AbstractFor autonomous Lotka–Volterra systems of differential equations modelling the dynamics of n competing species, new criteria are established for the existence of a single point global attractor. Under the conditions of these criteria, some of the species will survive and stabilise at a steady state whereas the others, if any, will die out ...
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

An Enhanced Quantum-Behaved Particle Swarm Optimization Based on a Novel Computing Way of Local Attractor

open access: yesInformation, 2015
Quantum-behaved particle swarm optimization (QPSO), a global optimization method, is a combination of particle swarm optimization (PSO) and quantum mechanics.
Pengfei Jia, Shukai Duan, Jia Yan
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Pullback D-Attractor of Coupled Rod Equations with Nonlinear Moving Heat Source

open access: yesJournal of Applied Mathematics, 2014
We consider the pullback D-attractor for the nonautonomous nonlinear equations of thermoelastic coupled rod with a nonlinear moving heat source. By Galerkin method, the existence and uniqueness of global solutions are proved under homogeneous boundary ...
Danxia Wang, Jianwen Zhang, Yinzhu Wang
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Exponential attractors for a Cahn-Hilliard model in bounded domains with permeable walls

open access: yesElectronic Journal of Differential Equations, 2006
In a previous article [7], we proposed a model of phase separation in a binary mixture confined to a bounded region which may be contained within porous walls. The boundary conditions were derived from a mass conservation law and variational methods.
Ciprian G. Gal
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Global attractor of the extended Fisher-Kolmogorov equation in Hk spaces

open access: yesBoundary Value Problems, 2011
The long-time behavior of solution to extended Fisher-Kolmogorov equation is considered in this article. Using an iteration procedure, regularity estimates for the linear semigroups and a classical existence theorem of global attractor, we prove that the
Luo Hong
doaj  

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