Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Global attractor in competitive Lotka–Volterra systems [PDF]
AbstractFor autonomous Lotka–Volterra systems of differential equations modelling the dynamics of n competing species, new criteria are established for the existence of a single point global attractor. Under the conditions of these criteria, some of the species will survive and stabilise at a steady state whereas the others, if any, will die out ...
openaire +3 more sources
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Existence and regularity of a global attractor for doubly nonlinear parabolic equations
In this paper we consider a doubly nonlinear parabolic partial differential equation $$ frac{partial eta (u)}{partial t}-Delta _{p}u+f(x,t,u)=0 quad hbox{in }Omega imesmathbb{R}^{+}, $$ with Dirichlet boundary condition and initial data given.
Abderrahmane El Hachimi, Hamid El Ouardi
doaj
Global dynamics of a fourth-order parabolic equation describing crystal surface growth
In this paper, we study the global dynamics for the solution semiflow of a fourth-order parabolic equation describing crystal surface growth. We show that the equation has a global attractor in H4per(Ω) when the initial value belongs to H1per(Ω).
Ning Duan, Xianyun Xu
doaj +1 more source
Viral Infection Model with Diffusion and Distributed Delay: Finite-Dimensional Global Attractor. [PDF]
Rezounenko A.
europepmc +1 more source
Regularity of trajectory attractor and upper semicontinuity of global attractor for a 2D non-Newtonian fluid [PDF]
There are two results within this paper. The one is the regularity of trajectory attractor and the trajectory asymptotic smoothing effect of the incompressible non-Newtonian fluid on 2D bounded domains, for which the solution to each initial value could ...
Shengfan Zhou +5 more
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Time-Dependent Global Attractor for a Class of Nonclassical Parabolic Equations
Based on the recent theory of time-dependent global attractors in the works of Conti et al. (2013) and di Plinio et al. (2011), we prove the existence of time-dependent global attractors as well as the regularity of the time-dependent global attractor ...
Fang-hong Zhang
doaj +1 more source

