Results 61 to 70 of about 54,142 (287)
Journal of Optimization, Differential Equations and Their ApplicationsWe investigate global resolvability and stability of attractors for parabolic inclusion with multi-valued interaction function of reaction-diffusion type and non-autonomous disturbances.
Oleksiy V. Kapustyan +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Capturing the non-stationarity of whole-brain dynamics underlying human brain states
NeuroImage, 2021 Brain dynamics depicts an extremely complex energy landscape that changes over time, and its characterisation is a central unsolved problem in neuroscience.
J.A. Galadí +8 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
About the Structure of Attractors for a Nonlocal Chafee-Infante Problem
Mathematics, 2021 In this paper, we study the structure of the global attractor for the multivalued semiflow generated by a nonlocal reaction-diffusion equation in which we cannot guarantee the uniqueness of the Cauchy problem.
Rubén Caballero +3 more
doaj +1 more source
Intrinsic strong shape of global attractors
Filomat, 2022 We present a proof of the strong shape theorem for global attractors in compact metric spaces using the intrinsic approach to strong shape from [18] which combines continuity over a covering and the corresponding homotopies of second order.
Nikita Shekutkovski, Martin Shoptrajanov
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Global dynamics of a reaction-diffusion system
Electronic Journal of Differential Equations, 2011 In this work the existence of a global attractor for the semiflow of weak solutions of a two-cell Brusselator system is proved. The method of grouping estimation is exploited to deal with the challenge in proving the absorbing property and the ...
Yuncheng You
doaj
Global Solutions and Asymptotic Study to a 3D-Lagrangian Boussinesq System
Journal of MathematicsWe prove that the Lagrangian-averaged 3D periodic Boussinesq system has a global in time weak solution that depends continuously on time. Also, we establish that a unique strong global in time solution exists.
Ridha Selmi, Faizah Dhami Alanazi
doaj +1 more source