Results 71 to 80 of about 54,142 (287)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Asymptotic behavior for second order lattice dynamical systems
Discrete Dynamics in Nature and Society, 2001 We consider the existence of the global attractor for a second order lattice dynamical systems.
Shengfan Zhou
doaj +1 more source
Finite dimensional attractor for a composite system of wave/plate equations with localised damping [PDF]
, 2010 The long-term behaviour of solutions to a model for acoustic-structure interactions is addressed; the system is comprised of coupled semilinear wave (3D) and plate equations with nonlinear damping and critical sources.
Bucci, Francesca, Toundykov, Daniel
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Global attractors for a class of degenerate diffusion equations
Electronic Journal of Differential Equations, 2003 In this paper we give two existence results for a class of degenerate diffusion equations with p-Laplacian. One is on a unique global strong solution, and the other is on a global attractor.
Shingo Takeuchi, Tomomi Yokota
doaj
The Existence of a Global Attractor for the S-K-T Competition Model with Self-Diffusion
Abstract and Applied Analysis, 2014 This paper concerns the uniform bounds of the global existence of solutions in time for the S-K-T competition model with self-diffusion.
Qian Xu, Ye Zhao
doaj +1 more source
Analytic Study of Shell Models of Turbulence
, 2005 In this paper we study analytically the viscous `sabra' shell model of energy turbulent cascade. We prove the global regularity of solutions and show that the shell model has finitely many asymptotic degrees of freedom, specifically: a finite dimensional
Aubin +35 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Global attractor and finite dimensionality for a class of dissipative equations of BBM's type
Electronic Journal of Differential Equations, 1998 In this work we study the Cauchy problem for a class of nonlinear dissipative equations of Benjamin-Bona-Mahony's type. We discuss the existence of a global attractor and estimate its Hausdorff and fractal dimensions.
M.A. Astaburuaga +3 more
doaj