Results 51 to 60 of about 8,017 (310)

Notes on the Global Attractors for Semigroup

International Journal of Modern Nonlinear Theory and Application, 2013
First we introduce two necessary and sufficient conditions which ensure the existence of the global attractors for semigroup. Then we recall the concept of measure of noncompactness of a set and recapitulate its basic properties. Finally, we prove that these two conditions are equivalent directly.
Yuhua Shi, Lan Xu
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Global attractors for p-Laplacian equation

Journal of Mathematical Analysis and Applications, 2007
AbstractThe existence of a (L2(Ω),W01,p(Ω)∩Lq(Ω))-global attractor is proved for the p-Laplacian equation ut−div(|∇u|p−2∇u)+f(u)=g on a bounded domain Ω⊂Rn (n⩾3) with Dirichlet boundary condition, where p⩾2. The nonlinear term f is supposed to satisfy the polynomial growth condition of arbitrary order c1|u|q−k⩽f(u)u⩽c2|u|q+k and f′(u)⩾−l, where q⩾2 is ...
Chengkui Zhong, Meihua Yang, Chunyou Sun
openaire   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Global dynamics of a reaction-diffusion system

Electronic Journal of Differential Equations, 2011
In this work the existence of a global attractor for the semiflow of weak solutions of a two-cell Brusselator system is proved. The method of grouping estimation is exploited to deal with the challenge in proving the absorbing property and the ...
Yuncheng You
doaj  

Global attractor for a nonlinear viscoelastic model

Journal of Mathematical Analysis and Applications, 2008
AbstractIn this paper we establish the existence of global attractors of a semiflow and a semigroup for a nonlinear 1-d viscoelasticity in two frameworks. We exploit the properties of the analytic semigroup to show the compactness for the semiflow and semigroup generated by the weak global solutions.
Yuming Qin, Tzon-Tzer Lu
openaire   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

On Global Attractors for a Class of Parabolic Problems [PDF]

Applied Mathematics & Information Sciences, 2014
This paper is devoted to study the existence of global attractor in H 1 0 (Ω) and uniform bounds of it in L ∞ (Ω) for a class of parabolic problems with homogeneous boundary conditions wich involves a uniform strongly elliptic operator of second order in the domain Ω R n .
Figueroa-López, Rodiak, Lozada-Cruz, German   +1 more
openaire   +2 more sources