Results 91 to 100 of about 43,348 (288)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Cross diffusion systems on n spatial dimensional domains

open access: yesElectronic Journal of Differential Equations, 2003
We show that there exists a global attractor for a triangular cross diffusion system with Lotka-Volterra reaction given on a two dimensional domain.
Dung Le
doaj  

Compact Global Chaotic Attractors of Discrete Control Systems

open access: yesNonautonomous Dynamical Systems, 2014
The paper is dedicated to the study of the problem of existence of compact global chaotic attractors of discrete control systems and to the description of its structure. We consider so called switched systems with discrete time xn+1 = fv(n)(xn), where v:
Cheban David
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A survey on impulsive dynamical systems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
In this survey we provide an introduction to the theory of impulsive dynamical systems in both the autonomous and nonautonomous cases. In the former, we will show two different approaches which have been proposed to analyze such kind of dynamical systems
Everaldo Bonotto   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Global attractors for damped semilinear wave equations

open access: yesDiscrete and Continuous Dynamical Systems, 2003
The nonlinear damped wave equation \[ u_{tt}+\beta u_t-\Delta u+f(u)=0 \] is considered on a bounded domain \(\Omega\subset {\mathbb R}^n\) imposing Dirichlet boundary conditions. For the nonlinearity it is assumed that \(\liminf_{| u| \to\infty}f(u)/u>-\lambda_1\), with \(\lambda_1\) the first eigenvalue of \(-\Delta\).
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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