Results 71 to 80 of about 4,601 (266)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
On the strongly damped wave equation and the heat equation with mixed boundary conditions
Abstract and Applied Analysis, 2000 We study two one-dimensional equations: the strongly damped wave equation and the heat equation, both with mixed boundary conditions. We prove the existence of global strong solutions and the existence of compact global attractors for these equations in ...
Aloisio F. Neves
doaj +1 more source
Global attractors for semigroup actions
Journal of Mathematical Analysis and Applications, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Souza, Josiney A. +1 more
openaire +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Shigesada-Kawasaki-Teramoto model on higher dimensional domains
Electronic Journal of Differential Equations, 2003 We investigate the existence of a global attractor for a class of triangular cross diffusion systems in domains of any dimension. These systems includes the Shigesada-Kawasaki-Teramoto (SKT) model, which arises in population dynamics and has been studied
Dung Le +2 more
doaj
Global attractor in competitive Lotka–Volterra systems [PDF]
Mathematische Nachrichten, 2009 AbstractFor autonomous Lotka–Volterra systems of differential equations modelling the dynamics of n competing species, new criteria are established for the existence of a single point global attractor. Under the conditions of these criteria, some of the species will survive and stabilise at a steady state whereas the others, if any, will die out ...
openaire +3 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Multistability in Large Scale Models of Brain Activity.
PLoS Computational Biology, 2015 Noise driven exploration of a brain network's dynamic repertoire has been hypothesized to be causally involved in cognitive function, aging and neurodegeneration.
Mathieu Golos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source