Results 41 to 50 of about 6,420 (267)

A Small-Amplitude Control Method of the Nonlinear Energy Sink Vibration Absorption System

Shock and Vibration, 2022
The nonlinear energy sink (NES) is an effective method to weaken or eliminate the line spectra feature of ship machinery equipment. However, due to the strong nonlinearity of the NES, there are multistable attractors in the NES vibration absorption ...
Qingchao Yang, Shuang Li, Jingjun Lou
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Global compact attractors and complete bounded trajectories for compressible magnetohydrodynamic system of equations [PDF]

Theoretical and Applied Mechanics
In this article, we investigate the global behavior of magnetohydrodynamic (MHD) fluid’s weak solutions in three-dimensional bounded domain with a compact Lipschitz boundary driven by arbitrary forces.
Muhammad Jan
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Bifurcations and Invariant Sets in a Class of Two-Dimensional Endomorphisms

International Journal of Analysis and Applications, 2019
Several endomorphisms of the plane have been constructed by simple maps. We study the dynamics occuring in one of them, which is rich in global bifurcations.
Djellit Ilham, Fakroune Yamina, Selmani Wissame   +2 more
doaj   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Global Attractors in H1(ℝN) for Nonclassical Diffusion Equations

Discrete Dynamics in Nature and Society, 2012
We study the existence of global attractors for nonclassical diffusion equations in H1(ℝN). The nonlinearity satisfies the arbitrary order polynomial growth conditions.
Qiao-zhen Ma, Yong-feng Liu, Fang-hong Zhang   +2 more
doaj   +1 more source

Attractors for the nonclassical reaction–diffusion equations on time-dependent spaces

Boundary Value Problems, 2020
In this paper, based on the notation of time-dependent attractors introduced by Conti, Pata and Temam in (J. Differ. Equ. 255:1254–1277, 2013), we prove the existence of time-dependent global attractors in H t $\mathcal{H}_{t}$ for a class of ...
Kaixuan Zhu, Yongqin Xie, Feng Zhou
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source