Results 51 to 60 of about 21,597 (261)

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Global Bifurcation of a Novel Computer Virus Propagation Model

Abstract and Applied Analysis, 2014
In a recent paper by J. Ren et al. (2012), a novel computer virus propagation model under the effect of the antivirus ability in a real network is established.
Jianguo Ren, Yonghong Xu, Jiming Liu
doaj   +1 more source

Global bifurcation for nonlinear Dirac problems

Electronic Journal of Qualitative Theory of Differential Equations, 2016
In this paper we consider the nonlinear eigenvalue problems for the one-dimensional Dirac equation. To exploit oscillatory properties of the components of the eigenvector-functions of linear one-dimensional Dirac system an appropriate family of sets is ...
Ziyatkhan Aliyev, Humay Rzayeva
doaj   +1 more source

Path-connectedness in global bifurcation theory

Electronic Research Archive, 2021
A celebrated result in bifurcation theory is that global connected sets of non-trivial solutions bifurcate from trivial solutions at non-zero eigenvalues of odd algebraic multiplicity of the linearized problem when the operators involved are compact. In this paper a simple example is constructed which satisfies the regularity hypotheses of the global ...
openaire   +3 more sources

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Bifurcation Analysis of a Lotka-Volterra Mutualistic System with Multiple Delays

Abstract and Applied Analysis, 2014
A class of Lotka-Volterra mutualistic system with time delays of benefit and feedback delays is introduced. By analyzing the associated characteristic equation, the local stability of the positive equilibrium and existence of Hopf bifurcation are ...
Xin-You Meng, Hai-Feng Huo
doaj   +1 more source

Global Hopf bifurcation in the ZIP regulatory system [PDF]

Journal of Mathematical Biology, 2014
Regulation of zinc uptake in roots of Arabidopsis thaliana has recently been modeled by a system of ordinary differential equations based on the uptake of zinc, expression of a transporter protein and the interaction between an activator and inhibitor.
Claus, Juliane, Ptashnyk, Mariya, Bohmann, Ansgar, Chavarría-Krauser, Andrés   +3 more
openaire   +5 more sources

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Global Bifurcation for Fractional $p$-Laplacian and an Application [PDF]

Zeitschrift für Analysis und ihre Anwendungen, 2016
We prove the existence of an unbounded branch of solutions to the non-linear non-local equation (-\Delta)^s_p u=\lambda |u|^{p-2}u + f(x,u,\lambda) \quad\text{in } \Omega,\quad u=0 \quad\text{in } \mathbb R^n\setminus\Omega ,
del Pezzo, Leandro Martin, Quaas, Alexander   +1 more
openaire   +3 more sources

Beyond Electrostatics: Anion‐π+ Orbital Hybridization Underpins High‐Performance Chloride Storage in Poly(arylamine) Organic Cathodes

Advanced Science, EarlyView.
The fundamental nature of anion storage in p‐type organic cathodes is elucidated using rigid poly(arylamine) frameworks. This study reveals a hybrid covalent‐ionic mechanism for anion‐π+ interactions, driven by synergistic orbital hybridization and electrostatic attraction.
Tiantian She, Jiena Weng, Jie Wang, Qiao Xi, Yangyang Zhang, Zijie Zhang, Zongqiong Lin, Wei Huang   +7 more
wiley   +1 more source