Results 101 to 110 of about 3,182 (259)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Orlicz-Sobolev inequalities and the Dirichlet problem for infinitely degenerate elliptic operators
Electronic Journal of Differential Equations, 2021 Usman Hafeez +3 more
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Stability and absorbing set of parabolic chemotaxis model of Escherichia coli
Nonlinear Analysis, 2013 This paper is devoted to model (1) for escherichia coli, introduced in [1]. Based on the experimental observations of Budrene and Berg [2, 3], Tyson and coworkers derived (1) with n cell density, c chemotrattactant concentration and s stimulant ...
Salvatore Rionero, Maria Vitiello
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Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Sufficient Conditions for Global Boundedness of Solutions for Two Coupled Synchronverters
2024 IEEE 63rd Conference on Decision and Control (CDC)This paper analyzes two synchronverters connected in parallel to a common capacitive-resistive load through resistive-inductive power lines. This system is conceptualized as a microgrid with two renewable energy sources controlled using the synchronverter algorithm.
Mercado Uribe, José Ángel +3 more
openaire +2 more sources
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Global boundedness and stability for a chemotaxis model of Boló's concentric sclerosis
Mathematical Biosciences and Engineering, 2020 A version of chemotaxis based mathematical model of the concentric sclerosis -- an inflammatory demyelinating disease -- studied in [\textit{V. Calvez} and \textit{R. H. Khonsari}, Math. Comput. Modelling 47, No. 7--8, 726--742 (2008; Zbl 1134.92019)] is considered.
Xiaoli Hu, Shengmao Fu
openaire +2 more sources