Results 121 to 130 of about 64,779 (321)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Boundedness in a chemotaxis system with consumption of chemoattractant and logistic source
Electronic Journal of Differential Equations, 2013 In this article, we consider a chemotaxis system with consumption of chemoattractant and logistic source $$\displaylines{ u_t=\Delta u-\chi\nabla\cdot(u\nabla v)+f(u),\quad x\in \Omega,\; t>0,\cr v_t=\Delta v-uv,\quad x\in\Omega,\; t>0, }$$ under ...
Liangchen Wang +2 more
doaj
Boundedness of the Global Error of Some Linear and Nonlinear Methods for Volterra Integral Equations [PDF]
, 2000 Antonia Vecchio
openalex +1 more source
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Boundedness of solutions to quasilinear elliptic systems
Advances in Nonlinear AnalysisThis article deals with elliptic systems of the form −∑i=1n∂∂xi∑β=1N∑j=1nai,jα,β(x,u(x))∂uβ(x)∂xj=fα(x),α=1,…,N.-\mathop{\sum }\limits_{i=1}^{n}\frac{\partial }{\partial {x}_{i}}\left(\mathop{\sum }\limits_{\beta =1}^{N}\mathop{\sum }\limits_{j=1}^{n}{a ...
Mi Fang +3 more
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source