Results 101 to 110 of about 2,018,671 (309)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Gastrointestinal nematodes of Ovis aries in Eastern Cape, South Africa and an evaluation of current anthelmintic procedures [PDF]

open access: yes, 2015
Humans have known about helminth infections since ancient times. Today half of the human population is plagued by a nematode infection. Nematodes are responsible for billions of dollars in global crop damage annually and have had devastating effects on ...
Rowell, Melyssa
core   +1 more source

Revisiting global fossil fuel and biofuel emissions of ethane [PDF]

open access: yes, 2017
Recent measurements over the Northern Hemisphere indicate that the long-term decline in the atmospheric burden of ethane (C2H6) has ended and the abundance increased dramatically between 2010 and 2014.
Blake, DR   +18 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Spatial analysis of neglected diseases in Brazil, 2007 to 2009

open access: yesTempus Actas de Saúde Coletiva, 2016
This paper aims to describe a set of epidemiological information regarding the spatial distribution of selected neglected diseases in Brazil from 2007 to 2009 and health care infrastructure and socio-economic indicators 2010.
Joyce Mendes de Andrade Schramm   +5 more
doaj   +1 more source

Challenges and Solutions for Functional Neurosurgery in Developing Countries. [PDF]

open access: yes, 2018
Functional neurosurgery techniques remain integral to the neurosurgical treatment armamentarium but data on global implementation remains scarce. In comparison to high-income countries (HIC), low- and middle-income countries (LMIC) suffer from an ...
Fezeu, Francis   +5 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Headache-Attributed Lost Time (HALT) Indices: measures of burden for clinical management and population-based research

open access: yesThe Journal of Headache and Pain, 2018
Background The burden attributable to headache disorders has multiple components: a simple measure summarising them all does not exist. The Migraine Disability Assessment (MIDAS) instrument has proved useful, estimating productive time lost in the ...
T. J. Steiner   +2 more
doaj   +1 more source

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