Results 111 to 120 of about 2,018,671 (309)
Sharing the Burden of GHG Reductions [PDF]
, 2008 and PDF report are also available on the MIT Joint Program on the Science and Policy of Global Change website (http://globalchange.mit.edu/).The G8 countries propose a goal of a 50% reduction in global emissions by 2050, in an effort that needs to take ...
Babiker, Mustafa M.H. +3 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Economic benefit of tuberculosis control [PDF]
Tuberculosis is the most important infectious cause of adult deaths after HIV/AIDS in low- and middle-income countries. This paper evaluates the economic benefits of extending the World Health Organization's DOTS Strategy (a multi-component approach that
Adeyi, Olusoji +5 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Factors leading to excessive fatigue in nurses – a three-year follow-up study
BMC NursingBackground Global nursing shortages necessitate the identification of mitigatable factors that may reduce nursing absence and turnover. Fatigue has been shown to be associated with these issues. This study aimed to identify factors leading to development
Stand Hiestand +4 more
doaj +1 more source
Strong evidence for negligible methyl chloroform (CH3CCl3) emissions from biomass burning [PDF]
, 2007 With the phase-out of industrial methyl chloroform (MCF) production, the atmospheric burden of this ozone-depleting gas has rapidly declined. Therefore any non-industrial sources are taking on greater significance in the MCF budget.
Andersen, MPS +5 more
core
The Global Burden of Occupational Disease [PDF]
Current Environmental Health Reports, 2017 Burden of occupational disease estimation contributes to understanding of both magnitude and relative importance of different occupational hazards and provides essential information for targeting risk reduction. This review summarises recent key findings and discusses their impact on occupational regulation and practice.New methods have been developed ...
openaire +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Global burden of stroke: an underestimate [PDF]
The Lancet, 2014 1 Feigin VL, Forouzanfar MH, Krishnamurthi R, et al. Global and regional burden of stroke during 1990–2010: fi ndings from the Global Burden of Disease Study 2010. Lancet 2014; 383: 245–55. 2 Strandberg TE, Pitkala KH, Tilvis RS, O’Neill D, Erkinjuntti TJ. Geriatric syndromes–vascular disorders? Ann Med 2013; 45: 265–73.
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source