Results 161 to 170 of about 2,018,671 (309)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The global burden of traumatic brain injury in adolescents and young adults, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. [PDF]

Ann Med
Chen Y, Yang J, Zhang N, Tong M, Chen L, Li Y, Dong W, Li X, Wang Y, Ren B, Zhang K.   +10 more
europepmc   +1 more source

European perspectives on global imbalances [PDF]

Alan Ahearne and Jürgen von Hagen explore the options European policy makers have in the context of global current account imbalances. Some Europeans are concerned that a disproportionately large burden of adjustment will fall on Europe when the ...
Alan Ahearne, Jürgen von Hagen
core   +1 more source

Global burden of postoperative death [PDF]

The Lancet, 2019
Dmitri Nepogodiev, Janet Martin, Bruce Biccard, Alex Makupe, Aneel Bhangu, Dmitri Nepogodiev, Janet Martin, Bruce Biccard, Alex Makupe, Adesoji Ademuyiwa, Adewale Oluseye Adisa, Maria-Lorena Aguilera, Sohini Chakrabortee, J. Edward Fitzgerald, Dhruva Ghosh, James C. Glasbey, Ewen M. Harrison, J.C. Allen Ingabire, Hosni Salem, Marie Carmela Lapitan, Ismail Lawani, David Lissauer, Laura Magill, Rachel Moore, Daniel C. Osei-Bordom, Thomas D. Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah Rayne, Sudha Sundar, Stephen Tabiri, Azmina Verjee, Raul Yepez, O. James Garden, Richard Lilford, Peter Brocklehurst, Dion G. Morton, Aneel Bhangu   +37 more
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Global burden of cardiovascular disease attributable to lead exposure: based on the global burden of disease study 2021. [PDF]

Front Public Health
Lin Z, Zhang Z, Zeng Q, Luo S, Xu J.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Bidirectional effect of poverty and treatment-resistant diseases: The case of antimicrobial resistance in middle and low-income countries

Journal of Infection and Public Health
Fakher Rahim
doaj   +1 more source

Global burden of neonatal respiratory infections attributable to air pollution: a systematic analysis based on the global burden of disease 2021 study. [PDF]

Eur J Pediatr
Wang Y, Cai F, Jiang X.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source