Results 181 to 190 of about 2,018,671 (309)

Potential effect of real-world junk food and sugar-sweetened beverage taxes on population health, health system costs and greenhouse gas emissions in New Zealand: a modelling study

BMJ Nutrition, Prevention & Health
Tony Blakely, Anja Mizdrak, Cliona Ni Mhurchu, Amanda C Jones, Nhung Nghiem, Leah Grout, Christine Cleghorn   +6 more
doaj   +1 more source

Evaluation and projection of the global burden of thyroid cancer from 1990 to 2035: an analysis based on the Global Burden of Disease Study. [PDF]

Thyroid Res
Wang L, Li R, Zeng X, Zhang H.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021. [PDF]

Korean J Intern Med
GBD 2021 AEMT Collaborators.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Global Burden of Vertebral Fractures in Women by Menopausal Status, 1990-2021, With 2050 Projections: An Analysis of Global Burden of Disease 2021. [PDF]

Global Spine J
Fan J, Liu W, Li G, Ji K, Wang L, Lian X, Wang Y, Jian Y.   +7 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Global burden of ischemic heart disease from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 and predictions to 2030. [PDF]

Chin Med J (Engl)
Jing S, Chen A, Xia Y, Ma J, Lu D, Chen Z, Qian J, Ge J.   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Global Burden of Type 2 Diabetes Attributable to Behavioral Risks: Insights and Projections to 2050 Based on the Global Burden of Disease Study 2021. [PDF]

Int J Public Health
Zhang G, Mei H, Sheng Q, Chen Y, Zhang X, Diwon A, Wang H, Chen Y, Wang Z, Zhang X, Mao Q, Li D, Zheng C, Mao G, Shi F.   +14 more
europepmc   +1 more source