Results 131 to 140 of about 13,279,908 (401)

Environmental Crisis and Sustainable Development: An Islamic Perspective in the Light of Shariah Objectives

open access: yesپاکستان جرنل آف اسلامک فلاسفی, 2023
Assistant Professor, Department of Islamic Studies, University of Engineering & Technology ...
Dr. Hafiz Qudrat Ullah
doaj  

Territories and global challenges [PDF]

open access: yes, 2017
Territories and their interdependencies are experiencing a reorganization in the wake of globalization. Traditional North-South divides are becoming blurred and new dynamics are at work in the context of pressing global challenges, such as climate change,
Pesche, Denis   +2 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Challenge of Global Challenges [PDF]

open access: yesGlobal Challenges, 2018
Jörn Ritterbusch   +5 more
openaire   +3 more sources

Paths Forward for the Global Water, Sanitation, and Hygiene (WASH) Sector [PDF]

open access: yes, 2010
The report summarizes key challenges and recommendations discussed at an event entitled "Paths Forward for the Global Water, Sanitation, and Hygiene (WASH) Sector" hosted by the Global Water Futures Project at the Center for Strategic and International ...

core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

SME Development in Malaysia: Domestic and Global Challenges [PDF]

open access: yes
The primary objectives of this paper are to analyze and discuss the development of Malaysian SMEs and their role, as well as various contributions, in the national economy.
Ndubisi, Nelson Oly, Saleh, Ali Salman
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Global problems in education as a research object in international databases: a historical perspective

open access: yesОбразование и наука
Introduction. Global problems of modernity and globalisation are appealing to scientists as a research subject not only for understanding their nature, development, and manifestations in various spheres of life (in the case of our study, in education ...
S. N. Sinegubov   +4 more
doaj   +1 more source

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