Results 91 to 100 of about 6,655,877 (292)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Uncertainty, Climate Change and the Global Economy [PDF]
The paper illustrates how one may assess our comprehensive uncertainty about the various relations in the entire chain from human activity to climate change.
Persson, Torsten, von Below, David
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Global Change: International Agreements on Youth [PDF]
, 2001 Summarizes the sections of the World Program of Action for Youth that focus on education, employment, health, girls and young women, and participation.
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Communications Earth & EnvironmentThe Durban floods of 11–12 April 2022 is the worst flood disaster in South Africa’s history and raised questions about the role of climate change in the event. Meso-scale dynamics, involving processes that cannot be resolved at the spatial resolutions of
Francois A. Engelbrecht +11 more
doaj +1 more source
The Evolution of a Global Climate Change Agreement [PDF]
This paper argues that while a long-term solution to climate change may require the global market-based solution envisioned in the Kyoto Protocol, a more flexible near-term approach is necessary.
Pizer, William A.
core
Climatic system as constituent of naturally- resource potential of economy [PDF]
, 2007 Social and ecological and economic consequences and damage, related to the change of climate require making of taking measures on adaptation to these changes and softening of their consequences, that will allow economic to ground made decisions on the ...
Telepenko, Irina
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Implications of and possible responses to climate change [PDF]
, 2009 Climate change is expected to worsen food insecurity and seriously undermines rural development prospects. It makes it harder to achieve the Millenium Development Goals and ensure a sustainable future beyond 2015.
Kahiluoto, Helena, Rötter, Reimund
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