Results 81 to 90 of about 12,171,189 (307)

Global Climate Change Impacts in the United States [Highlights]

, 2009
This booklet highlights key findings from the Global climate Change Impacts in the United States. a state of knowledge report about the observed and projected consequences of climate change for our nation and people.
U.S. Global Change Research Program
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Multi-model assessment of regional climate simulations over Pakistan using SMHI RCA4 downscaled global climate models under the CORDEX framework

Discover Atmosphere
We present an evaluation and future projections of ten Global Climate Models (GCMs) dynamically downscaled using Rossby Centre Regional Atmospheric model version 4 (RCA4) under the Coordinated Regional Climate Downscaling Experiment (CORDEX) framework ...
Qudsia Zafar, Shahbaz Mehmood, Muhammad Adnan, Nadia Rehman, Muhammad Farooq Iqbal, Muhammad Amjad   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Building trust in large-scale water quality models: 13 alternative strategies beyond validation

Discover Water
Validating large-scale water quality models is challenging because of the variety of water quality constituents, and scales for which observations are limited.
Maryna Strokal, Mengru Wang, Ilaria Micella, Annette B. G. Janssen   +3 more
doaj   +1 more source

Our changing planet : the FY ... research plan

, 1994
Annual report of the U.S. Global Change Research Program documenting activities and progress, goals for the upcoming year, proposed budget considerations, and other information about the organization for fiscal year ...
U.S. Global Change Research Program
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Limited increases in Arctic offshore oil and gas production with climate change and the implications for energy markets

Scientific Reports
Climate change impacts on sea ice thickness is opening access to offshore Arctic resources. The degree to which these resources are exploited will depend on sea-ice conditions, technology costs, international energy markets, and the regulatory ...
Ying Zhang, Siwa Msangi, James Edmonds, Stephanie Waldhoff   +3 more
doaj   +1 more source

U.S. Global Change Research Program: Social Science Highlights [PDF]

A pamphlet about the U.S. Global Change Research Program (USGCRP). The program coordinates and integrates global change research across 13 federal government agencies to ensure that it most effectively serves the Nation and the ...
United States. Global Change Research Program.
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source