Results 91 to 100 of about 12,171,189 (307)
npj Climate ActionSince public support is critical for implementing carbon pricing policies, we conduct a systematic review and meta-analysis to examine the survey-based literature on change in public support for direct and indirect carbon pricing policies with and ...
Farah Mohammadzadeh Valencia +5 more
doaj +1 more source
Journal of Advances in Modeling Earth Systems, 2018 Modeling the aerosol lifecycle in traditional global climate models (GCM) is challenging for a variety of reasons, not the least of which is the coarse grid.
Guangxing Lin +10 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Our Changing Planet: The FY 1995 U.S. Global Change Research Program
, 1994 The U.S. GLOBAL CHANGE RESEARCH PROGRAM (USGCRP) supports activities that provide information and policy-relevant understanding about the coupling of human activities and the environment across a broad range of issues, perspectives, and interactions ...
U.S. Global Change Research Information Office
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2017 Water shortages are now affecting half the world’s population, disrupting food and energy security as well as urban water supplies in many cities. The overuse of water and associated drying of rivers, lakes, and aquifers has become a leading cause of ...
Richter, Brian D.
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Global Climate Change Impacts in the United States
, 2009 This brochure highlights a report that summarizes the science of climate change, and the impacts of climate change on the United ...
U.S. Global Change Research Program
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The U.S. Climate Change Science Program Vision for the Program and Highlights of the Scientific Strategic Plan [PDF]
, 2003 The vision document provides an overview of the Climate Change Science Program (CCSP) long-term strategic plan to enhance scientific understanding of global climate change.This document is a companion to the comprehensive Strategic Plan for the Climate ...
Climate Change Science Program and the Subcommittee on Global Change Research
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